Changes of PTH, 1,25（OH）2D3 and Biochemistry in Renal Osteodystrophy.

The changes of plasma PTH, 1,25（OH）D, serum calcium, phosphorus and AKP were observed in 55 uremic patients with renal osteodystrophy. The results showed that: in all types of renal osteodystrophy, plasma PTH were markedly higher than normal （P<0.001）, while plasma 1,25（OHH）Dand serum calcium were lower than normal （P<0.001）. In low bone-turnover uremic osteodystrophy （LTO）, plasma phosphorus was markedly lower than that of high bone-turnover uremic osteodystrophy （HTO） and mixe d uremic osteodystrophy （MO） （P<0.05）, and plasma 1,25（OH）Dwas significantly lower than that of HTO （P<0.05）. In HTO and MO, serum phosphorus was much higher than mormal （P<0.001）. Plasma PTH had a negative linear correlation with plasma 1,25（OH）D（P<0.05）, a positive linear correlation with serum AKP （P<0.05）, but no linear correlation with the duration of hemodialysis, serum calcium, serum aluminum and bone aluminum content. Plasma 1.25（OH）Dhad no linear correlation with the duration of hemodialysis, seru