With the increasing demands of aircraft design,the traditional deterministic design can hardly meet the requirements of fine design optimization because uncertainties may exist throughout the whole lifecycle of the aircraft. To enhance the robustness and reliability of the aircraft design, Uncertainty Multidisciplinary Design Optimization( UM DO) has been developing for a long time. This paper presents a comprehensive reviewof UM DO methods for aerospace vehicles,including basic UM DO theory and research progress of its application in aerospace vehicle design. Firstly,the UM DO theory is preliminarily introduced,with giving the definition and classification of uncertainty as well as its sources corresponding to the aircraft design. Then following the UM DO solving process, the application in different coupled disciplines is separately discussed during the aircraft design process,specifically clarifying the UM DO methods for aerostructural optimization. Finally,the main challenges of UM DO and the future research trends are given.