Sperm antigen MSH27 participates in sperm-egg membrane fusion

被引:0
|
作者
ZHUANG Dazhong
机构
关键词
spermatozoon; membrane fusion; monoclonal antibody; antigen;
D O I
暂无
中图分类号
Q492 [生殖生理学];
学科分类号
090501 ;
摘要
A monoclonal antibody (mAb), MSH27 has been selected from an mAb library which has been prepared with separated mouse sperm heads as antigens. Three aspects of evidence indicated that the MSH27 antigen was involved in the process of sperm-egg membrane fusion. After the acrosome reaction, the antigen was located at sperm equatorial segment and in postacrosomal area, where, it was widely accepted, the sperm-egg membrane fusion initially
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页码:1483 / 1489
页数:7
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