Synthesis, Structure, and DNA Binding of a Platinum(Ⅱ) Complex Based on the 3,4,5-Trimethoxy-phenyl-1H-imidazo[4,5-f][1,10]phenanthroline

被引：2
|
作者：
黎晓 [1 ,2 ]
罗旭健 [2 ]
杨燕 [2 ]
马利 [1 ]
王书龙 [2 ]
罗志辉 [2 ]
刘荣军 [2 ]
梁伟江 [2 ]
机构：
[1] College of Chemistry & Chemical Engineering,Chongqing University
[2] Guangxi Key Lab of Agricultural Resources Chemistry and Biotechnology,Colleges and Universities Key Laboratory for Efficient Use of Agricultural Resources in the Southeast of Guangxi,College of Chemistry and Food Science,Yulin Normal University
来源：
结构化学 | 2018年 / 37卷 / 05期
基金：
中国国家自然科学基金;
关键词：
platinum complex; DNA interaction; UV-Vis absorption;
D O I：
10.14102/j.cnki.0254-5861.2011-1812
中图分类号：
O641.4 [络合物化学（配位化学）];
学科分类号：
070304 ; 081704 ;
摘要：
A new platinum(Ⅱ) complex of [Pt(chda)(3,4,5-triopip)]Cl·2HO(1) based on 3,4,5-trimethoxy-phenyl-1 H-imidazo[4,5-f][1,10]phenanthroline(3,4,5-triopip) has been synthesized by hydrothermal methods and its consequences are characterized by elemental analysis, IR, single-crystal X-ray diffraction, UV-Vis absorption and fluorescent spectrum. The UV-Vis absorption studies reveal that the molecule undergoes considerable interaction with the nucleic acid. In this mononuclear structure, the platinum adopts a four-coordinated square planar geometry, which may favor the intercalation between the neighboring bases of the G-quadruplex(G4) DNA.
引用
收藏
页码：811 / 818
页数：8
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