Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome

被引：0
|
作者：
Farhad Sahebjam [1 ]
Cristina H Hajdu [2 ]
Esther Nortey [1 ]
Samuel H Sigal [1 ,3 ]
机构：
[1] Division of Gastroenterology, New York University School of Medicine
[2] Department of Pathology, New York University School of Medicine
[3] Division of Gastroenterology and Liver Diseases, Montefiore Medical Center and Albert Einstein College of Medicine
来源：
World Journal of Hepatology | 2016年 / 14期
关键词：
Hepatitis C; Autoimmune hepatitis; Overlap syndrome; Direct acting antiviral therapy;
D O I：
暂无
中图分类号：
R512.63 []; R575.1 [肝炎];
学科分类号：
1002 ; 100201 ; 100401 ;
摘要：
Autoimmune phenomena are common in patients with chronic hepatitis C. Management of chronic hepatitis C/autoimmune hepatitis syndrome has until recently been problematic due to the adverse effects of interferon on autoimmune processes and immunosuppression on viral replication. In this report we describe 3 patients with chronic hepatitis C/autoimmune hepatitis overlap syndrome who responded rapidly to direct acting antiviral therapy. The resolution of the autoimmune process supports a direct viral role in its pathophysiology.
引用
收藏
页码：632 / 636
页数：5
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