Involvement of T-complex protein 1-ring complex/chaperonin containing T-complex protein 1(TRiC/CCT) in retrograde axonal transport through tau phosphorylation

被引:0
|
作者
Xu-Qiao Chen [1 ]
机构
[1] Department of Neurosciences, University of California San Diego
关键词
TRiC/CCT; in retrograde axonal transport through tau phosphorylation;
D O I
暂无
中图分类号
R338 [神经生理学];
学科分类号
0710 ; 071006 ;
摘要
The cytosolic chaperonin T-complex protein 1-ring complex(TRiC)or chaperonin containing T-complex protein 1(CCT)is essential in de novo folding of approximately 10%of the eukaryotic,newly translated polypeptides as well as misfolded proteins.There is a close link between the TRiC/CCT cytosolic chaperonin and neurodegenerative diseases(Lopez et al.,2015).A lot of research suggests that CCT
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页码:588 / 590
页数:3
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