Particle motion trajectory tracking based on fiber optic tweezers

被引:0
|
作者
ZHAO Cun [1 ]
DONG Taiji [2 ]
GAO Bingkun [2 ]
LIU Xu [2 ]
ZHANG Zihua [3 ]
机构
[1] Department of Electrical Information Engineering, Northeast Petroleum University Qinhuangdao Campus
[2] College of Electrical and Information Engineering, Northeast Petroleum University
[3] Faculty of Materials and Manufacturing, Beijing University of Technology
基金
中国国家自然科学基金;
关键词
D O I
暂无
中图分类号
TN253 [光纤元件]; TP212.3 [生物传感器、医学传感器];
学科分类号
0702 ; 070207 ; 080202 ;
摘要
A biosensor based on single-fiber optical tweezers is proposed, which can detect the motion trajectory of cells based on the stable capture and transmission of silica microspheres as well as biological yeast cells by using a tapered optical fiber as a sensing element. The interference cavity is formed by using the fiber tip and the target particle, the detected interference signal is demodulated using Hilbert transform, and the displacement curve of the particle is plotted to realize the particle motion trajectory tracking. This method provides potential technical support for process monitoring of targeted drug delivery in biomedicine.
引用
收藏
页码:462 / 467
页数:6
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