Overlap of diabetic ketoacidosis and hyperosmolar hyperglycemic state

被引:0
|
作者
Esraa Mamdouh Hassan [1 ]
Hisham Mushtaq [2 ]
Esraa Elaraby Mahmoud [3 ]
Sherley Chhibber [4 ]
Shoaib Saleem [5 ]
Ahmed Issa [6 ]
Jain Nitesh [1 ]
Abbas B Jama [1 ]
Anwar Khedr [7 ]
Sydney Boike [8 ]
Mikael Mir [8 ]
Noura Attallah [1 ]
Salim Surani [9 ]
Syed A Khan [1 ,10 ]
机构
[1] Anesthesiolgy,Mayo Clinic
[2] Critical Care Medicine,Mayo Clinic Health System
[3] Medicine,St.Vincent's Medical Center
[4] Medicine,College of Medicine,University of Sharjah
[5] Medicine,Mercy Catholic Medical Center  5. Medicine,Mayo Hospital  6. Medicine,Medical University of the Americas 
[6] Medicine,University of Minnesota Medical School
[7] Medicine & Pharmacology,Texas A&M University Health Science Center
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中图分类号
R587.2 [糖尿病性昏迷及其他并发症];
学科分类号
1002 ; 100201 ;
摘要
Diabetic ketoacidosis(DKA) and hyperosmolar hyperglycemia state(HHS) are two life-threatening metabolic complications of diabetes that significantly increase mortality and morbidity.Despite major advances,reaching a uniform consensus regarding the diagnostic criteria and treatment of both conditions has been challenging.A significant overlap between these two extremes of the hyperglycemic crisis spectrum poses an additional hurdle.It has well been noted that a complete biochemical and clinical patient evaluation with timely diagnosis and treatment is vital for symptom resolution.Worldwide,there is a lack of large-scale studies that help define how hyperglycemic crises should be managed.This article will provide a comprehensive review of the pathophysiology,diagnosis,and management of DKA-HHS overlap.
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页码:11702 / 11711
页数:10
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