Clinical features of elderly patients with COVID-19 in Wuhan, China

被引:0
|
作者
Shuo Wei [1 ]
Guang Chen [2 ,3 ]
Xiao-Chun Ouyang [3 ,4 ]
Yuan-Cheng Hong [3 ,5 ]
Yun-Hu Pan [2 ,3 ]
机构
[1] Department of Infectious Disease, Shengli Clinical Medical College of Fujian Medical University, Fujian Provincial Hospital
[2] Department of Respiratory Medicine, 907 Hospital of the Joint Logistics Team
[3] No. 4 Infection Department Second Ward, Wuhan Huoshenshan Hospital
[4] Department of Respiratory Medicine, 908 Hospital of the Joint Logistics Team
[5] Department of Respiratory Medicine, 910 Hospital of the Joint Logistics Team
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中图分类号
R563.1 [肺炎];
学科分类号
1002 ; 100201 ;
摘要
BACKGROUND Elderly patients with coronavirus disease 2019(COVID-19) who have comorbidities, frailty or profound disabilities experience poor outcomes. We analyzed the clinical characteristics of elderly patients from Wuhan who had COVID-19 during the early stages of the pandemic.AIM To identify factors affecting the early mortality of elderly patients with COVID-19.METHODS The records of 234 patients who were 65-years-old or more and were hospitalized in Wuhan Huoshenshan Hospital from February 4 to March 4, 2020 were reviewed. All patients had confirmed COVID-19 and the final date of follow-up was April 4, 2020.RESULTS There were 163 cases of mild disease(69.66%), 39 cases of severe disease(16.67%) and 32 cases of critical disease(13.68%). Twenty-nine patients died within 1 mo(12.40%), all of whom had critical disease. Surviving patients and deceased patients had no significant differences in age or chronic diseases. Overall, the most common symptoms were fever(65.4%), dry cough(57.3%), fatigue(47.4%)and shortness of breath(41%). The deceased patients had higher levels of multiple disease markers(C-reactive protein, D-dimer, lactate dehydrogenase, alanine amino transferase, aspartate aminotransferase, creatinine kinase and creatinine kinase-MB) and higher incidences of lymphocytopenia and hypoproteinemia.CONCLUSION This single-center study of elderly patients from Wuhan, China who were hospitalized with COVID-19 indicated that age and chronic diseases were not associated with mortality. Hypertension, diabetes and cardiovascular disease were the most common comorbidities and the most common symptoms were fever, dry cough, fatigue and shortness of breath. Lymphocytopenia, increased levels of D-dimer and other markers indicative of damage to the heart, kidneys or liver were associated with an increased risk of death.
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页码:12890 / 12898
页数:9
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