Purpose:This study compared the effects of pupil variation on light detection and temporal modulation across the central visual field.Methods:Light detection sensitivity (LDS) and low flickering frequency (6Hz) temporal modulation sensitivity(TMS) of 20 young subjects were measured from the central visual field of the right eyes using an automated perimeter (Medmont M600). The measurements were taken under 3 artificial pupils, i.e. 3mm, 4.3mm and 6mm diameters. The sensitivities were grouped and averaged for different retinal eccentricities(3°, 6°, 10° and 15°).Results:TMS and LDS were reduced with increasing retinal eccentricities (P<0.001) and decreasing pupil diameters(P<0.001). TMS collected from all pupil diameters were significantly different from each other(P<0.001). Similarly, LDS under 3mm pupil was statistically different from those of 4.3mm and 6mm(P<0.003). Comparison of the hills of vision showed that pupil variation resulted in significantly different slopes (P=0.001). The slopes were