Schistosoma japonicum Eggs Exerts Protective Effects in an Experimental Ulcerative Colitis Model

被引:0
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作者
MA Zhen Rong [1 ]
SUN Xi [1 ,2 ]
ZHENG Wen Xiao [1 ,3 ]
LI Xuan Wu [1 ]
ZHANG Ni [1 ]
HUANG Ye Hong [1 ]
LU Bin [1 ]
LI Zhuo Lin [1 ]
NOUHOUM Di Bo [1 ]
YU Xin Ling [4 ]
ZHOU Jie [4 ]
CHEN Hong Zhi [5 ]
YANG Xue Xian [6 ]
WU Xiang [1 ]
机构
[1] Department of Parasitology, School of Basic Medical Sciences, Xiangya School of Medicine, Central South University
[2] Department of Urology, Second Affiliated Hospital of Sun Yat-sen University
[3] Clinical Medicine, Xiangya School of Medicine, Central South University
[4] Hunan Institute of Parasite Disease, WHO Collaborating Center For Research and Control on Schistosomiasis in Lake Region
[5] National Clinical Research Center for Metabolic Disease, Key Laboratory of Diabetes Immunology, Ministry of Education, and Department of Metabolism and Endocrinology, The Second Xiangya Hospital, Central South University
[6] Department of Molecular & Genetic and Microbiology, University of New Mexico School of Medicine
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中图分类号
R574.62 [结肠疾病];
学科分类号
摘要
Ulcerative colitis(UC) is a chronic inflammatory disease affecting the colon, with an increasing incidence worldwide. Disease pathogenesis is multifactorial and involves genetic predisposition,epithelial barrier defects, dysregulated immune responses, and environmental factors[1,2]. Longstanding UC leads to several complications such as megacolon, inflammation of the eye and joints,
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页码:1085 / 1089
页数:5
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