Role of IQGAP1 in mediating angiotensin Ⅱ-induced apoptosis of podocytes and its underlying mechanism

被引：0
|
作者：
刘以鹏 [1 ]
机构：
[1] Div Nephrol,Renmin Hosp,Wuhan Univ
来源：
China Medical Abstracts (Internal Medicine) | 2014年 / 31卷 / 02期
关键词：
time; Role of IQGAP1 in mediating angiotensin; JNK; ERK;
D O I：
暂无
中图分类号：
R692 [肾疾病];
学科分类号：
1002 ; 100210 ;
摘要：
Objective To investigate the role of IQ domain GT Pase-activating protein 1(IQGAP1)in angiotensinⅡ(AngⅡ)-induced podocyte apoptosis and the underlying mechanism.Methods Differentiated mouse podocytes were exposed to AngⅡat different concentrations for 6 h or at 10-8mol/L for variable incubation time.Podocyte apoptosis was assessed by flow cytometry.Expression o
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页码：112 / 113
页数：2
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