The role of Keap1/Nrf2/HO-1 signal pathway in liver injury induced by rare earth neodymium oxide in mice

被引：0
|
作者：
卜宁 [1 ]
机构：
[1] Sch Public Health,Baotou Med Coll
来源：
China Medical Abstracts (Internal Medicine) | 2023年 / 40卷 / 02期
关键词：
D O I：
暂无
中图分类号：
R114 [卫生毒理];
学科分类号：
100405 ;
摘要：
Objective To investigate the role of Keapl/Nrf2/HO-1 signaling pathway in liver injury induced by neodymium oxide(Nd2O3) in mice.Methods In March2021,forty-eight SPF grade healthy male C57BL/6J mice were randomly divided into control group(0.9%NaCl),low dose group(62.5 mg/ml Nd2O3),medium dose group(125.0 mg/ml Nd2O3),and high dose group(250.0 mg/ml Nd203),each group with 12.The infected groups were treated with Nd2O3suspension by non-exposed tracheal drip and were killed 35 days after dust exposure.
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页码：82 / 83
页数：2
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