The Wnt/β-catenin signaling:a multifunctional target for neuroprotective and regenerative strategies in Parkinson's disease

被引：0
|
作者：
Annalucia Serafino [1 ]
Mauro Cozzolino [1 ]
机构：
[1] Institute of Translational Pharmacology-National Research Council of Italy
来源：
Neural Regeneration Research | 2023年 / 02期
关键词：
D O I：
暂无
中图分类号：
R742.5 [震颤麻痹综合征];
学科分类号：
1002 ;
摘要：
Parkinson’s disease (PD) is the most frequent movement disorder and the second most prevalent age-related neurodegenerative disease (ND) worldwide.From the clinical point of view,it is characterized by severe motor complications,including uncontrollable resting tremors,rigidity,bradykinesia,and postural instability.These motor symptoms are caused by the selective and progressive degeneration of midbrain dopaminergic neurons in the subtantia nigra pars compacta and their striatal projections (Kalia and Lang,2015),
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页码：306 / 308
页数：3
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