Objective: Parkinson’s disease is a degenerative disease that has impaired movement, resting tremble, bradykinesia, muscle rigidity, and altered gait and balance of the body.The electrodiagnostic by Ryodoraku is a resource to evaluate balance to meridians through the bioelectrical conductivity expressed in specific acupoints.The aim of this study was to evaluate the profile of energy meridians by electrodiagnostic Ryodoraku in patients with Parkinson’s disease.Methods: This study was conducted in Curitiba/Brazil, with 37 subjects of both sexes, with a mean age of 62 years with stage 1 to 4, according to the scale and modified Hoehn & Yahr(2001).Electronic system biodiagnostic NKL trademark, model EL 608 omnipax with 12 V, frequency 1 to 10 Hz, 200 μA was used.Results: The subjects of initial pathological stages showed energy imbalance deficiency that is more evident in the Sanjiao meridian(22.7% of imbalances).In more advanced stages of the Parkinson’s disease, subjects appeared more evident stagnation in the spleen meridian(30% of imbalances).A decrease occurred in the average bioelectrical conductivity from 29 A in the early stage of the disease to 17.5 A in the later stage.Conclusion: It is concluded that there are energy profile characteristics that can be evaluated by electrodiagnostic Ryodoraku in patients with Parkinson’s disease, and a deficiency of vital energy with worsening of the disease.