Selenium Supplementation Alleviates Autoimmune Thyroiditis by Regulating Expression of Th1/Th2 Cytokines

被引:0
|
作者
TAN Long [1 ]
SANG Zhong Na [1 ]
SHEN Jun [2 ]
WU Yun Tang [1 ]
YAO Zhai Xiao [1 ]
ZHANG Jin Xiang [1 ]
ZHAO Na [1 ]
ZHANG Wan Qi [1 ]
机构
[1] Nutrition and Food Security Department, College of Public Health, Tianjin Medical University, 22 Qixiangtai Road,Heping District
[2] Sanitary Chemistry Department, College of Public Health, Tianjin Medical University, 22 Qixiangtai Road,Heping District
基金
中国国家自然科学基金;
关键词
Th; AITD; Selenium Supplementation Alleviates Autoimmune Thyroiditis by Regulating Expression of Th1/Th2 Cytokines; TPOAb; Figure;
D O I
暂无
中图分类号
R581.4 [甲状腺炎];
学科分类号
1002 ; 100201 ;
摘要
Selenium (Se) is an essential trace element.Autoimmune thyroid diseases (AITD) are destructive inflammatory or anti-receptor autoimmune diseases characterized by reactivity to self-thyroid antigens.However,the effects of Se on the cytokines in AITD are still unclear.So we researched the role of Selenium (Se) and Th1/Th2 cytokine productions in the pathogenesis of autoimmune thyroid diseases (AITD).The data shown that high Se intake reduced the autoantibody titers and alleviated the pathological
引用
收藏
页码:920 / 925
页数:6
相关论文
共 50 条
  • [1] Selenium Supplementation Alleviates Autoimmune Thyroiditis by Regulating Expression of Th1/Th2 Cytokines
    Tan Long
    Sang Zhong Na
    Shen Jun
    Wu Yun Tang
    Yao Zhai Xiao
    Zhang Jin Xiang
    Zhao Na
    Zhang Wan Qi
    BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2013, 26 (11) : 920 - 925
  • [2] Differential involvement of Th1 and Th2 cytokines in autoimmune diseases
    Kroemer, G
    Hirsch, F
    GonzalezGarcia, A
    Martinez, C
    AUTOIMMUNITY, 1996, 24 (01) : 25 - 33
  • [3] Role of Th1/Th2 cells and related cytokines in autoimmune hepatitis
    Behfarjam, Farinaz
    Sanati, Mohammad Hossein
    Nasseri-Moghaddam, Siavash
    Ataei, Mitra
    Nikfam, Sepideh
    Jadali, Zohreh
    TURKISH JOURNAL OF GASTROENTEROLOGY, 2017, 28 (02): : 110 - 114
  • [4] Th1/Th2 cytokines in psoriasis
    Jadali, Z.
    Izad, M.
    Eslami, M. B.
    Mansouri, P.
    Safari, R.
    Bayatian, P.
    Mirshafiey, A.
    Nodeh, A. R. Salehi
    IRANIAN JOURNAL OF PUBLIC HEALTH, 2007, 36 (02): : 87 - 91
  • [5] Cytokine production regulating Th1 and Th2 cytokines in hemophagocytic lymphohistiocytosis
    Osugi, Y
    Hara, J
    Tagawa, S
    Takai, K
    Hosoi, G
    Matsuda, Y
    Ohta, H
    Fujisaki, H
    Kobayashi, M
    Sakata, N
    KawaHa, K
    Okada, S
    Tawa, A
    BLOOD, 1997, 89 (11) : 4100 - 4103
  • [6] Expression of Th1 and Th2 immunoregulatory cytokines by human eosinophils
    Woerly, G
    Roger, N
    Loiseau, S
    Capron, M
    INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY, 1999, 118 (2-4) : 95 - 97
  • [7] Tetrathiomolybdate inhibits experimental autoimmune encephalomyelitis by balancing Th2/Th1 cytokines
    Hou, Guoqing
    Zeng, Chunhua
    Dick, Robort
    Brewer, George J.
    ANNALS OF NEUROLOGY, 2007, 62 : S70 - S70
  • [8] Profile of Th1/Th2 Cytokines in Autoimmune Pulmonary Alveolar Proteinosis.
    Inoue, Y.
    Matsumuro, A.
    Hirose, M.
    Arai, T.
    Otsuka, J.
    Sugimoto, C.
    Minamoto, S.
    Nishiyama, A.
    Sugiyama, K.
    Nakagawa, M.
    Kitaichi, M.
    Akira, M.
    Hayashi, S.
    Nakata, K.
    Okada, M.
    Sakatani, M.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2009, 179
  • [9] RELATIONSHIP BETWEEN THE Th1/Th2 CYTOKINES IMBALANCE AND AUTOIMMUNE THYROID DISEASES
    Tang, Ya Mei
    Chen, Zhi Heng
    Tang, Ai Guo
    CELL BIOLOGY INTERNATIONAL, 2008, 32 (03) : S51 - S51
  • [10] Re: The role of Th1/Th2 cells and associated cytokines in autoimmune hepatitis
    Akkoc, Tunc
    TURKISH JOURNAL OF GASTROENTEROLOGY, 2017, 28 (02): : 115 - 116