SARS-CoV-2 Omicron variant (B.1.1.529):A concern with immune escape

被引:0
|
作者
Adekunle Sanyaolu [1 ]
Aleksandra Marinkovic [2 ]
Stephanie Prakash [2 ]
Nafees Haider [3 ]
Martina Williams [2 ]
Chuku Okorie [4 ]
Olanrewaju Badaru [5 ]
Stella Smith [6 ]
机构
[1] Department of Public Health, Federal Ministry of Health  2. Department of Basic Sciences, Saint James School of Medicine  3. Department of Basic
[2] Department of Molecular Biology and Biotechnology, Nigerian Institute of Medical Research
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中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Omicron,the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)variant that is now spreading across the world,is the most altered version to emerge so far,with mutations comparable to changes reported in earlier variants of concern linked with increased transmissibility and partial resistance to vaccineinduced immunity.This article provides an overview of the SARS-CoV-2 variant Omicron (B.1.1.529) by reviewing the literature from major scientific databases.Although clear immunological and clinical data are not yet available,we extrapolated from what is known about mutations present in the Omicron variant of SARS-CoV-2 and offer preliminary indications on transmissibility,severity,and immune escape through existing research and databases.
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页码:137 / 143
页数:7
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