Molecular genetic studies of familial Meniere's disease

被引：1

作者：

Jing Zhang ^{[1
,2
]}

Jing Guan ^{[1
]}

Hongyang Wang ^{[1
]}

Dayong Wang ^{[1
]}

Lidong Zhao ^{[1
]}

Huifang Zhou ^{[2
]}

Qiuju Wang ^{[1
]}

机构：

[1] Chinese PLA Institute of Otolaryngology,Chinese PLA General Hospital,Medical School of Chinese PLA

[2] Department of Otolaryngology of Tianjin Medical University General Hospital

来源：

Science China Life Sciences | 2019年 / 11期

基金：

中国国家自然科学基金;

关键词：

MD; Molecular genetic studies of familial Meniere’s disease;

D O I：

暂无

中图分类号：

R764.3 [内耳疾病];

学科分类号：

100213 ;

摘要：

Dear Editor.Meniere’s disease (MD,MIM 156000),a chronic clinical illness affecting the inner ear,presents as episodes of spontaneous vertigo,fluctuating sensorineural hearing loss,tinnitus,and aural fullness.Endolymphatic hydrops in the cochlear duct and vestibular organs is considered the underlying histopathologic characteristic of MD.Most MD cases are sporadic (sporadic Meniere’s disease,SMD),and approximately 4%-20%of patients with MD have a familial history.Familial Meniere’s disease (FMD) is defined as the clinical symptoms of at least one patient’s relative (first-or

引用

页码：1557 / 1560

页数：4

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