Study on Left Ventricular Diastolic Function under Different Left Ventricular Systolic Function

Objectives Assessment of diastolic function is vital to impart information relevant to patientscardiac functional class, diagnosis and management. We sought to investigate diastolic function under normal systolic function and systolic dysfunction and pseudonormalized phenomena. Methods 36 normal subjects(Group I),33 patients with coronary artery disease(CAD)(Group II)and 74 patients with essential hypertension(EH)(Group III)were studied by color M mode Doppler echocardiography. The rate of propagation of peak early filling flow velocity(Vp),time delay(TD)of the peak early filling flow velocity from mitral tips to the apex, Vp/E and other parameters were measured by color M mode Doppler echocardiography. Results Three groups had no statistical differences in gender, age and heart rate. There were significant differences of Vp, TD and Vp/E ratio between systolic dysfunction group and normal systolic function group. The result also showed significant differences in Vp, TD and Vp/E between pseudonormal group and control group(P< 0.01). Conclusion The rate and time of propagation of peak early filling flow velocity (Vp, TD, Vp/E) by M-mode color Doppler echocardiography are more precise and reliable parameters to evaluate LV diastolic function by distinguishing pseudonormalized transmitral flow pattern.