Objective:Ovarian cancer has the highest mortality rate of all gynecologic tumors. We compared the survival rate of ovarian cancer patients with different histological types and different time periods,aiming to elucidate the therapeutic effect and provide more evidence for the prevention and treatment of ovarian cancer.Methods:605 patients with ovarian cancer who underwent surgery at Qilu Hospital,Shandong University from September 1998 to August2012 were retrospectively reviewed. The 5-year survival rate was calculated in epithelial ovarian cancer(EOC)and non-epithelial ovarian cancer(Non-EOC). In addition,the patients were divided into two groups according to time at diagnosis(September 1998 to August 2007 and September 2007 to August 2012). The difference of 5-year survival rate between these two periods was compared.Results:The 5-year overall survival rate of all patients with ovarian cancer was59. 2% from September 1998 to August 2012. The survival rate of patients with EOC was lower(63. 0%)than that of Non-EOC(90. 8%). For both histological types,the 5-year survival rate of patients with localized disease(90. 8%)was significantly higher than that of patients with distant-stage(57. 6%). For different time periods,there was no significant difference in 5-year survival rate between ovarian cancer with different stages.Conclusion:Histological types and stages are closely related to survival of patients with ovarian cancer. More comprehensive clinical and follow-up information could provide convincing evidence for the prevention and treatment of ovarian cancer.
