Electromyographic evaluation of functional electrical stimulation to injured oculomotor nerve

被引:0
|
作者
Massimiliano Visocchi [1 ]
机构
[1] Institute of Neurosurgery, Catholic University Medical School, Policlinico Gemelli Largo Gemelli, Rome, Italy
基金
中国国家自然科学基金;
关键词
electrical stimulation; electromyogram; oculomotor nerve; motor unit potential; injury; evaluation; neural regeneration;
D O I
暂无
中图分类号
R779.1 [眼损伤与异物];
学科分类号
100212 ;
摘要
Functional electrical stimulation delivered early after injury to the proximal nerve stump has been proposed as a therapeutic approach for enhancing the speed and specificity of axonal regeneration following nerve injury. In this study, the injured oculomotor nerve was stimulated functionally by an implantable electrode. Electromyographic monitoring of the motor unit potential of the inferior oblique muscle was conducted for 12 weeks in two injury groups, one with and one without electric stimulation. The results revealed that, at 2, 4, 6, 8 weeks after functional electric stimulation of the injured oculomotor nerve, motor unit potentials significantly increased, such that amplitude was longer and spike duration gradually shortened. These findings indicate that the injured oculomotor nerve has the potential for regeneration and repair, but this ability is not sufficient for full functional recovery to occur. Importantly, the current results indicated that recovery and regeneration of the injured oculomotor nerve can be promoted with functional electrical stimulation.
引用
收藏
页码:870 / 875
页数:6
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