Study on the establishment of immune thrombocytopenia model induced by anti-platelet GP Ⅰ bα antibodies

被引:0
|
作者
周康熙 [1 ]
机构
[1] 1st Afil Hosp,Soochow Univ
关键词
ITP; antibodies; Study on the establishment of immune thrombocytopenia model induced by anti-platelet GP;
D O I
暂无
中图分类号
R558.2 [];
学科分类号
1002 ; 100201 ;
摘要
Objective To establish primary immune thrombocytopenia(ITP)animal model induced by anti-platelet membrane glycoprotein GPⅠbαantibodies AN51 and R300.Methods Twenty guinea pigs(6-8 week)were divided into 4 groups.Five guinea pigs in each group were intravenously injected with different doses of AN51(0.05,0.1,0.2μg/g)and 0.2μg/g Ig G as control.
引用
下载
收藏
页码:183 / 183
页数:1
相关论文
共 50 条
  • [1] Indirect detection of anti-platelet antibodies in immune thrombocytopenia
    Zheng, Shiying Silvia
    Perdomo, Jose Sail
    Ahmadi, Zohra
    Chong, Beng Hock
    PATHOLOGY, 2021, 53 (06) : 759 - 762
  • [2] Administration of Anti-Platelet Antibodies Prevents the Anti-Platelet Immune Response and Bleeding Complications of Neonatal Immune Thrombocytopenia in a Murine Model
    Tiller, Heidi
    Chen, Pingguo
    Skogen, Bjorn
    Killie, Mette Kjaer
    Husebekk, Anne
    Matviyenko, Maryana
    Kjeldsen-Kragh, Jens
    Ni, Heyu
    BLOOD, 2009, 114 (22) : 97 - 97
  • [3] Anti-Platelet Antibodies Are Predominantly IgM in Childhood Immune Thrombocytopenia
    Schmidt, David
    Heitink-Polle, Katja M. J.
    Porcelijn, Leendert
    Van der Schoot, C. Ellen
    Vidarsson, Gestur
    Bruin, Marrie
    De Haas, Masja
    BLOOD, 2017, 130
  • [4] Detection of anti-platelet antibodies in immune thrombocytopenia by flow cytometry
    Teraz-Orosz, Adrienn
    Cooper, Nichola
    Crawley, James T. B.
    Salles-Crawley, Isabelle I.
    BRITISH JOURNAL OF HAEMATOLOGY, 2019, 184 (05) : 844 - 847
  • [5] Anti-platelet antibodies in childhood immune thrombocytopenia: Prevalence and prognostic implications
    Schmidt, David E.
    Heitink-Polle, Katja M. J.
    Porcelijn, Leendert
    van der Schoot, C. Ellen
    Vidarsson, Gestur
    Bruin, Marrie C. A.
    de Haas, Masja
    JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 2020, 18 (05) : 1210 - 1220
  • [6] QUANTITATION OF ANTI-PLATELET ANTIBODIES BY RADIOIMMUNOASSAY IN SERA OF PATIENTS WITH IMMUNE THROMBOCYTOPENIA
    ROMANO, EL
    PASCUAL, CJ
    SUAREZ, G
    HAEMATOLOGICA, 1981, 66 (05) : 597 - 604
  • [7] Severe Thrombocytopenia Induced by Vancomycin-Dependent Anti-Platelet Antibodies
    Swanenberg, Irene
    Bhalla, Samir
    Altshuler, Diana
    Adelman, Mark
    Colon, Lilith
    Sloane, Mark
    CHEST, 2017, 152 (04) : 299A - 299A
  • [8] Detection and dynamics of anti-platelet antibodies in thrombocytopenic dogs with and without idiopathic immune thrombocytopenia
    Shropshire, Sarah
    Dow, Steven
    Lappin, Michael
    JOURNAL OF VETERINARY INTERNAL MEDICINE, 2020, 34 (02) : 700 - 709
  • [9] Thrombocytopenia and anti-platelet antibodies in patients with chronic hepatitis C
    Pshenichnaya, N.
    Gopatza, G.
    Zhuravlev, A.
    INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2016, 45 : 453 - 453
  • [10] Vaccine-induced immune thrombocytopenia and thrombosis: The decline in anti-platelet factor 4 antibodies is assay-dependent
    Platton, Sean
    Schoenborn, Linda
    Charrot, Sarah
    Badat, Mohsin
    Boot, Jesca
    McDonald, Vickie
    Sivapalaratnam, Suthesh
    Bariana, Tadbir
    Theodoulou, Angela
    Bowles, Louise
    MacCallum, Peter
    BRITISH JOURNAL OF HAEMATOLOGY, 2022, 197 (04) : 428 - 430