Northern pig-tailed macaques (Macaca leonina) infected with SARS-CoV-2 show rapid viral clearance and persistent immune response

被引：0

作者：

Tian-Zhang Song ^{[1
]}

Hong-Yi Zheng ^{[1
]}

Jian-Bao Han ^{[2
]}

Xiao-Li Feng ^{[2
]}

Feng-Liang Liu ^{[1
]}

Xiang Yang ^{[2
]}

Lin Jin ^{[1
]}

Rong-Hua Luo ^{[1
]}

Ren-Rong Tian ^{[1
]}

Chao Liu ^{[3
]}

Ming-Hua Li ^{[2
]}

Hou-Rong Cai ^{[4
]}

Yong-Tang Zheng ^{[1
,2
,3
]}

机构：

[1] Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common Diseases, Kunming Institute

[2] Kunming National High-Level Biosafety Research Center for Non-Human Primates, Center for Biosafety Mega-Science,Kunming Institute of Zoology, Chinese Academy of Sciences

[3] National Resource Center for Non-Human Primates, and National Research Facility for Phenotypic & Genetic Analysis of Model Animals (Primate Facility), Kunming Institute of Zoology,Chinese Academy of Sciences

[4] Department of Respiratory and Critical Care Medicine, Affiliated Drum Tower Hospital of Nanjing University

来源：

Zoological Research | 2021年 / 42卷 / 03期

基金：

中国国家自然科学基金; 国家重点研发计划;

关键词：

Northern pig-tailed macaques; Macaca leonina; infected with SARS-CoV-2 show rapid viral clearance and persistent immune response;

D O I：

暂无

中图分类号：

R563.1 [肺炎]; R-332 [医用实验动物学];

学科分类号：

1001 ; 1002 ; 100201 ;

摘要：

Coronavirus disease 2019(COVID-19), which is caused by severe acute respiratory syndrome coronavirus(SARS-CoV-2), has become an unprecedented global health emergency.At present, SARS-CoV-2-infected nonhuman primates are considered the gold standard animal model for COVID-19 research. Here, we showed that northern pig-tailed macaques(Macaca leonina, NPMs) supported SARS-CoV-2 replication.Furthermore, compared with rhesus macaques,

引用

页码：350 / 353

页数：4

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[1] Northern pig-tailed macaques (Macaca leonina) infected with SARS-CoV-2 show rapid viral clearance and persistent immune response
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