Treatment of Metformin on women with polycystic ovary syndrome

被引：0

作者：

曹晓航 ^{[1
,2
]}

张俊吉 ^{[3
]}

施璧 ^{[2
]}

Rolando Martins ^{[2
]}

罗新 ^{[1
]}

机构：

[1] Department of Obstetrics & Gynecology,The First Affiliated Hospital of Jinan University(guangzhou)

[2] Department of Obstetrics & Gynecology,Centro Hospitalar Conde de Sao Januario(CHCSJ),Macau

[3] Department of Obstetrics & Gynecology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences

来源：

生殖医学杂志 | 2009年 / 18卷 / S2期

关键词：

Metformin; Polycystic ovary syndrome; Androgen;

D O I：

暂无

中图分类号：

R711.75 [卵巢疾病];

学科分类号：

100211 ;

摘要：

Polycystic ovary syndrome(PCOS) appears to be the most common endocrine disorders of women. It is associated with significant reproductive,endocrine,metabolic,and cardiovascular morbidity.Hyperinsuline-mia and insulin resistance,which result in hyperandrogenemia have been documented as a central role in the pathogenesis of PCOS.Treatment with insulin sensitizer,metformin,has been shown to follow by regularization of menstrual cycle,improved response to ovulation induction and reduction of hyperandrogenism.It possibly prevents early trimester pregnancy loss and decrease the risk of developing typeⅡdiabetes and cardiovascular disease.This article aims to review the current evidence on the use of metformin in women with PCOS.

引用

页码：85 / 89

页数：5

共 19 条

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