Anti-cancer Effect of 20(S)-Ginsenoside-Rh2 on Oral Squamous Cell Carcinoma Cells via the Decrease in ROS and Downregulation of MMP-2 and VEGF

被引：0

作者：

ZHANG Bao Ping ^{[1
,2
]}

LI Bo ^{[1
]}

CHENG Jing Yang ^{[1
]}

CAO Rui ^{[1
]}

GAO Shu Ting ^{[1
]}

HUANG Chun Juan ^{[1
]}

LI Rui Ping ^{[1
]}

NING Jing ^{[3
]}

LIU Bin ^{[1
]}

LI Zhi Ge ^{[1
]}

机构：

[1] School of Stomatology, Lanzhou University

[2] Institute of Biomechanics and Medical Engineering, Lanzhou University

[3] Department of Stomatology, Gansu Provincial Hospital

来源：

BiomedicalandEnvironmentalSciences | 2020年 / 33卷 / 09期

关键词：

D O I：

暂无

中图分类号：

R739.8 [口腔、颌面部肿瘤];

学科分类号：

100214 ;

摘要：

Squamous cell carcinoma(SCC) is the most common in oral and maxillofacial regions and occupy more than 90% of the malignant lesions in the oral cavity[1]. The complex anatomy of the head and neck region gives rise to intricate patterns of local invasion and regional spread, which makes primary tumors more difficult to eradicate.

引用

页码：713 / 717

页数：5

共 46 条

[1] Anti-cancer Effect of 20(S)-Ginsenoside-Rh2 on Oral Squamous Cell Carcinoma Cells via the Decrease in ROS and Downregulation of MMP-2 and VEGF
Zhang Bao Ping
Li Bo
Cheng Jing Yang
Cao Rui
Gao Shu Ting
Huang Chun Juan
Li Rui Ping
Ning Jing
Liu Bin
Li Zhi Ge
BIOMEDICAL AND ENVIRONMENTAL SCIENCES, 2020, 33 (09) : 713 - +
[2] The effect of blocking the expression of TGF-β and MMP-2 mRNA on oral squamous cell carcinoma cells.
Kim, S.-G.
Hong, S. P.
JOURNAL OF DENTAL RESEARCH, 2003, 82 : B25 - B25
[3] Participation of fibroblasts in MMP-2 binding and activation on the surface of oral squamous cell carcinoma cells
Hayashido, Y
Urabe, K
Yoshioka, Y
Kitano, H
Okamoto, T
Matsuya, T
INTERNATIONAL JOURNAL OF ONCOLOGY, 2003, 22 (03) : 657 - 662
[4] The identification of molecular target of (20S) ginsenoside Rh2 for its anti-cancer activity
Yu-Shi Wang
Yingjia Lin
He Li
Yang Li
Zhiguang Song
Ying-Hua Jin
Scientific Reports, 7
[5] The identification of molecular target of (20S) ginsenoside Rh2 for its anti-cancer activity
Wang, Yu-Shi
Lin, Yingjia
Li, He
Li, Yang
Song, Zhiguang
Jin, Ying-Hua
SCIENTIFIC REPORTS, 2017, 7
[6] Oral Squamous Cell Carcinoma Cells with Acquired Resistance to Erlotinib Are Sensitive to Anti-Cancer Effect of Quercetin via Pyruvate Kinase M2 (PKM2)
Chan, Chien-Yi
Hong, Shih-Cing
Chang, Chin-Ming
Chen, Yuan-Hong
Liao, Pin-Chen
Huang, Chun-Yin
CELLS, 2023, 12 (01)
[7] Anti-cancer and analgesic effects of resolvin D2 in oral squamous cell carcinoma
Ye, Yi
Scheff, Nicole N.
Bernabe, Daniel
Salvo, Elizabeth
Ono, Kentaro
Liu, Cheng
Veeramachaneni, Ratna
Viet, Chi T.
Viet, Dan T.
Dolan, John C.
Schmidt, Brian L.
NEUROPHARMACOLOGY, 2018, 139 : 182 - 193
[8] Ginsenoside Rh2 sensitizes the anti-cancer effects of sunitinib by inducing cell cycle arrest in renal cell carcinoma
Hyun Ji Hwang
Seong Hwi Hong
Hong Sang Moon
Young Eun Yoon
Sung Yul Park
Scientific Reports, 12
[9] Ginsenoside Rh2 sensitizes the anti-cancer effects of sunitinib by inducing cell cycle arrest in renal cell carcinoma
Hwang, Hyun Ji
Hong, Seong Hwi
Moon, Hong Sang
Yoon, Young Eun
Park, Sung Yul
SCIENTIFIC REPORTS, 2022, 12 (01)
[10] Ginsenoside Rh2 Inhibits Cancer Stem-Like Cells in Skin Squamous Cell Carcinoma
Liu, Shunli
Chen, Mingrui
Li, Pengcheng
Wu, Yujia
Chang, Chunjuan
Qiu, Yabin
Cao, Ling
Liu, Zhen
Jia, Chiyu
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY, 2015, 36 (02) : 499 - 508

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