Prochlorperazine and spasticity after spinal cord injury

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作者
Liabeuf S
Stuhl-Gourmand L
Gackière F
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中图分类号
R651.2 [脊髓];
学科分类号
1002 ; 100210 ;
摘要
BACKGROUND AND OBJECTIVE In mature neurons,low intracellular chloride(CL-)levels are required for post-synaptic inhibition,with these levels maintained by the potassium-chloride cotransporter,KCC2.After spinal cord injury(SCI),the disinhibition of motor neurons is linked to a dysfunction of KCC2,leading to a predisposition to spasticity.This study assessed the effects of different medications
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页码:186 / 186
页数:1
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