Mitochondria-targeted ratiometric fluorescent probes for micropolarity and microviscosity and their applications

被引：0
|
作者：
Jingjing Cui [1 ]
Yuhua Yao [1 ]
Cong Chen [1 ]
Rui Huang [1 ]
Weibing Zhang [1 ]
Junhong Qian [1 ]
机构：
[1] Shanghai Key Laboratory of Functional Materials Chemistry, School of Chemistry & Molecular Engineering, East China University of Science and Technology
来源：
Chinese Chemical Letters | 2019年 / 30卷 / 05期
基金：
中国国家自然科学基金;
关键词：
Fluorescent probe; Mitochondria; Microviscosity; Micropolarity;
D O I：
暂无
中图分类号：
O657.3 [光化学分析法（光谱分析法）];
学科分类号：
070302 ; 081704 ;
摘要：
Two fluorescent "off-on" probes YYH1 and YYH2 were used for the detection of mitochondrial polarity and viscosity. Both probes have two emission bands:The peak of shorter wavelength was sensitive to the polarity, while that in longer wavelength region was sensitive to the viscosity, which enables us to detect medium polarity and viscosity simultaneously. The lg(Ishort/Ilong) of YYH1 exhibited linear relationship to the solvent polarity, while that of YYH2 was closely related to the solvent viscosity. Furthermore, both probes showed potential in bioimaging mitochondrial polarity or viscosity in living cells.
引用
收藏
页码：1071 / 1074
页数：4
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