Capillary Electrophoretic Separation of Monosialogangliosides by using cyclodectrin and borax as selectors

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作者
By Using Cyclodextrin and Borax as SelectorsLi Wen CHANG
Zhao Lou YU
Gui Yun XU and Yi CHENInstitute of Chemistry Chinese Academy of Sciences Beijing [100080 ]
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关键词
Monosialogangliosides; using; Separation; Capillary;
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O652.6 [富集方法、分离方法];
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摘要
TOwhomco ̄ndenCeshouldbeaddreSSedBothMSGLSandCDcontainhydronylgroupsonadjacentcanonatoms.IthasbeenknownthatpolyhydroxycompoundscanformironiccomplexeswithboraxIS].B}'addingboraxtothebuffercontainingor-CD,thesepboonofMSGLSti.asimproveddr ̄cally.asshowninFig.1.ImprovementofselectivitywaspresUmabl}.duetocomplexationoftheMSGLSwithboraxanda-CDinthesolution.OurobservationsshowedthattheconcentrationofboraxandthePHinthebaerarecriticalfactorsthechngtheresoluhonofMSGLS.DecreasingtheconcentrationOfboraxfrom100to50amoks.
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