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EGFR;
NSCLC;
About the Cover;
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In more than one half of all patients with non-small cell lung cancer(NSCLC),the aberrant epidermal growth factor receptor(EGFR)signaling contributes to the oncogenic phenotype.During normal EGFR signaling,receptor activation is dependent on ligand-mediated receptor dimerization.Once the subunits dimerize,a series of phosphorylation events serve to enhance EGFR kinase activity to stimulate
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页码：148 / 148
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