Hirsutella sinensis antagonizes the effect of aristolochic acid on human proximal tubular epithelial cells

被引:0
|
作者
张媺 [1 ]
机构
[1] Center Nephrol China-Japan Friendship Hosp Beijing 100029
关键词
CTGF; HKC; Hirsutella sinensis antagonizes the effect of aristolochic acid on human proximal tubular epithelial cells;
D O I
暂无
中图分类号
R692 [肾疾病];
学科分类号
1002 ; 100210 ;
摘要
Objective To study whether Hirsutella sinensis (HS) can antagonize aristolochic acid (AA) induced fibrogenesis on human proximal tubular epithelial cells (HKC). Methods HKC were incubated with medium alone, medium with HS 10 mg/L, medium with AA-Na 40 mg/L or medium with AA-Na 40 mg/L and HS 10 mg/L, respectively. After 12 h (for mRNA) or 36 h (for protein) , cells were lysed, and the mRNA and pro-
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页码:223 / 224
页数:2
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