CLINICAL SIGNIFICANCE OF COMBINED ANTINUCLEAR AND ANTICYTOPLASMIC ANTIBODIES DETECTED BY IMMUNOFLUORESCENCE

被引：0
|
作者：
Tung-Kwang Lee
Henry Rothberger
机构：
[1] DepartmentofRadiationOncology,EastCarolinaUniversitySchoolofMedicine,Greenville,NorthCarolina27858,USA
[2] SectionofRheumatology,DepartmentofMedicine,BowmanGraySchoolofMedicineofWakeForestUniversity,Winston-Salem,NorthCar7103,USA
来源：
CHINESE MEDICAL JOURNAL | 1989年 / 12期
关键词：
D O I：
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中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
Anti-nuclear antibodies (ANA) combined with anti-cytoplasmic antibodies (ACA) in 0.6% (n=43) of 7 121 consecutive patients referred for ANA screening were observed. Homogeneous/cytoplasmic was the most frequently combined ANA/ACA pattern among 6 different indirect immunofluorescent (IF) combinations. Distribution of diseases was similar in patients with ANA/ACA and those controls with ANA alone. However, the ANA/ACA results were often transitory, especially in systemic lupus erythromatosus (SLE). The appearance of transitory ANA/ACA combinations on serial ANA testing may be useful as a serologic marker for SLE.
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