Association of dynamic functional connectivity with bilateral precuneus at resting-state with obsessive-compulsive disorder

Objective To investigate the dynamic functional connectivity (d FC) of bilateral precuneus at resting-state in obsessive-compulsive disorder (OCD). Methods Fifty patients with OCD who matched the criteria of ICD-10and 50 healthy controls (HCs) were examined by the resting-state functional magnetic resonance imaging scanning. Voxel-based whole-brain dFC method was used to analyze the dFC of bilateral precuneus at restingstate in OCD; Pearson correlation analyseis was used to analyze the relationship between the abnormal d FC values and clinical symptoms in OCD; support vector machine analysis was used to explore whether abnormal dFC could be used to identify OCD. Results Compared with HCs,