Dual PPAR delta/gamma agonist offer therapeutic potential for Alzheimer's disease

被引：0
|
作者：
Ian Steinke [1 ]
Meenakshi Singh [1 ]
Rajesh Amin [1 ]
机构：
[1] Department of Drug Discovery and Development,Auburn University
来源：
Neural Regeneration Research | 2024年 / 06期
关键词：
D O I：
暂无
中图分类号：
R749.16 [];
学科分类号：
100203 ;
摘要：
The increasing incidence of Alzheimer’s disease(AD) in the aging population, indicates the critical need for the development of novel targeted molecular therapies for ameliorating AD pathology. Moreover, clinical and preclinical evidence demonstrates that peroxisomal proliferator activating receptors(PPAR) agonists regulate energy and lipid homeostasis in models of diabetes, as well as improve spatial memory in animal models of AD(Khan et al., 2019).
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页码：1175 / 1176
页数：2
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