Alpha-Synuclein Handling by Microglia: Activating, Combating,and Worsening

被引：1
|
作者：
Ning Song [1 ,2 ]
Leilei Chen [2 ]
Junxia Xie [2 ]
机构：
[1] Department of Physiology, Shandong Provincial Key Laboratory of Pathogenesis and Prevention of Neurological Disorders, School of Basic Medicine, Qingdao University
[2] Institute of Brain Science and Disease, Qingdao University
来源：
Neuroscience Bulletin | 2021年 / 37卷 / 05期
关键词：
D O I：
暂无
中图分类号：
R741.02 [神经病理学、病因学];
学科分类号：
0710 ; 071006 ;
摘要：
Neuroinflammation and a-synuclein (a-syn) aggregation are both neuropathological hallmarks of Parkinson’s disease (PD). Microglia are crucial participants in eliciting neuroinflammatory responses themselves, as well as modulating neurotoxic activity in astrocytes, therefore forming a pathway to neurodegeneration induced by both central and peripheral insults [1, 2].
引用
收藏
页码：751 / 753
页数：3
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