Mitochondrial DNA methylation and mitochondria-related epigenetics in neurodegeneration

被引：0

作者：

Fabio Coppedè

机构：

[1] Department of Translational Research and of New Surgical and Medical Technologies, Laboratory of Medical Genetics, University of Pisa

[2] Interdepartmental Research Center of Biology and Pathology of Aging, University of Pisa

来源：

Neural Regeneration Research | 2024年 / 19卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R741.02 [神经病理学、病因学];

学科分类号：

0710 ; 071006 ;

摘要：

Mitochondria are cytoplasmic organelles referred to as the powerhouse of the cell because they are primarily involved in oxidative phosphorylation and energy production. They are particularly abundant in tissues with high energy demands, including muscle, liver, and brain, and mitochondrial dysfunction , oxidative mitochondrial DNA (mtDNA) damage, and impaired mitochondrial dynamics have often been associated with neurodegeneration.

引用

页码：405 / 406

页数：2

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