Utility of Polygenic Risk Scores: From Disease Risk Prediction to Evaluation of Germline-Somatic Associations

被引：0
|
作者：
Saito, Yuki [1 ,2 ]
Namba, Shinichi [3 ]
Kogure, Yasunori [1 ]
Okada, Yukinori [3 ,4 ,5 ]
Kataoka, Keisuke [1 ,6 ]
机构：
[1] Natl Canc Ctr, Res Inst, Div Mol Oncol, Tokyo, Japan
[2] Keio Univ, Sch Med, Dep Gastro, Tokyo, Japan
[3] Osaka Univ, Grad Sch Med, Dept Stat Genet, Osaka, Japan
[4] RIKEN, Ctr Integrat Med Sci, Lab Syst Genet, Wako, Saitama, Japan
[5] Univ Tokyo, Grad Sch Med, Dept Genome Informat, Tokyo, Japan
[6] Keio Univ, Sch Med, Dept Med, Div Hematol, Tokyo, Japan
来源：
CANCER SCIENCE | 2024年 / 115卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
S2-4
引用
收藏
页码：24 / 24
页数：1
相关论文
共 50 条
  • [1] Polygenic risk scores in atrial fibrillation: Associations and clinical utility in disease prediction
    Gibson, Joel T.
    Rudd, James H. F.
    HEART RHYTHM, 2024, 21 (06) : 913 - 918
  • [2] Somatic mutational profiles and germline polygenic risk scores in human cancer
    Yuxi Liu
    Alexander Gusev
    Yujing J. Heng
    Ludmil B. Alexandrov
    Peter Kraft
    Genome Medicine, 14
  • [3] Somatic mutational profiles and germline polygenic risk scores in human cancer
    Liu, Yuxi
    Gusev, Alexander
    Heng, Yujing J.
    Alexandrov, Ludmil B.
    Kraft, Peter
    GENOME MEDICINE, 2022, 14 (01)
  • [4] Polygenic risk scores for the prediction of cardiometabolic disease
    O'Sullivan, Jack W.
    Ashley, Euan A.
    Elliott, Perry M.
    EUROPEAN HEART JOURNAL, 2023, 44 (02) : 89 - 99
  • [5] The association between somatic mutational profiles and germline polygenic risk scores in TCGA
    Liu, Yuxi
    Gusev, Alexander
    Heng, Yujing J.
    Alexandrov, Ludmil B.
    Kraft, Peter
    CANCER RESEARCH, 2020, 80 (16)
  • [6] Polygenic Scores in Epidemiology: Risk Prediction, Etiology, and Clinical Utility
    Brion S. Maher
    Current Epidemiology Reports, 2015, 2 (4) : 239 - 244
  • [7] Polygenic Risk Scores: Genomes to Risk Prediction
    Hayeck, Tristan J.
    Busby, George B.
    Chun, Sung
    Lewis, Anna C. F.
    Roberts, Megan C.
    Vilhjalmsson, Bjarni J.
    CLINICAL CHEMISTRY, 2023, 69 (06) : 551 - 557
  • [8] Clinical utility of polygenic risk scores for coronary artery disease
    Derek Klarin
    Pradeep Natarajan
    Nature Reviews Cardiology, 2022, 19 : 291 - 301
  • [9] Clinical utility of polygenic risk scores for coronary artery disease
    Klarin, Derek
    Natarajan, Pradeep
    NATURE REVIEWS CARDIOLOGY, 2021, 19 (5) : 291 - 301
  • [10] Polygenic risk scores: a biased prediction?
    De La Vega, Francisco M.
    Bustamante, Carlos D.
    GENOME MEDICINE, 2018, 10
12345