Genome-wide association analysis reveals genetic loci and candidate genes for white diarrhea in Jingyuan chickens

被引：0
|
作者：
Yang, Lijuan [1 ]
Chen, Siyu [1 ]
Zhao, Wei [1 ]
Zhang, Guojun [2 ]
Zhang, Hu [2 ]
Zhang, Tong [1 ]
Xue, Lin [1 ]
Tian, Jinli [1 ]
Gu, Yaling [1 ]
Li, Lanlan [1 ]
Wang, Hu [1 ]
Zhang, Juan [1 ]
机构：
[1] Ningxia Univ, Coll Anim Sci & Technol, Yinchuan, Peoples R China
[2] Pengyang Cty Anim Dis Prevent & Control Ctr, Guyuan, Peoples R China
来源：
RESEARCH IN VETERINARY SCIENCE | 2025年 / 186卷
关键词：
Jingyuan chicken; SNPs; Chicken dysentery; Gwas; PULLORUM DISEASE; SALMONELLA; PRODUCTS; FORMAT;
D O I：
10.1016/j.rvsc.2025.105568
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
In order to investigate the basic genetic structure of dysentery in Jingyuan chickens and to explore the genetic markers associated with dysentery resistance in chickens, the present study was based on the genome-wide association analysis (GWAS) technique to investigate the candidate SNPs and genes associated with dysentery resistance in Jingyuan chickens, and a total of 12 SNPs were associated with dysentery resistance in Jingyuan chickens. In addition, some important candidate genes inciuding frizzled class receptor 4 (FZD4), DDB1 and CUL4 associated factor 13(DCAF13), regulating synaptic membrane exocytosis 2 (RIMS2), transmembrane protein 8C (TMEM8C), and RIC1 homolog (RIC1) were identified by selection signal analysis, gene annotation, and enrichment analysis. These results can be used as potential molecular selection markers for chicken dysentery resistance in Jingyuan chickens in order to improve the breeding of disease resistance in Jingyuan chickens.
引用
收藏
页数：10
相关论文
共 50 条
  • [1] Genome-wide association analysis reveals genetic loci and candidate genes associated with intramuscular fat in Duroc pigs
    Xingwang WANG
    Rongrong DING
    Jianping QUAN
    Linxue YANG
    Ming YANG
    Enqin ZHENG
    Dewu LIU
    Gengyuan CAI
    Zhenfang WU
    Jie YANG
    FrontiersofAgriculturalScienceandEngineering, 2017, 4 (03) : 335 - 341
  • [2] Genome-wide association analysis reveals genetic loci and candidate genes for meat quality traits in Chinese Laiwu pigs
    Xinwei Xiong
    Xianxian Liu
    Lisheng Zhou
    Jie Yang
    Bin Yang
    Huanban Ma
    Xianhua Xie
    Yixuan Huang
    Shaoming Fang
    Shijun Xiao
    Jun Ren
    Congying Chen
    Junwu Ma
    Lusheng Huang
    Mammalian Genome, 2015, 26 : 181 - 190
  • [3] Genome-wide association analysis reveals genetic loci and candidate genes for feeding behavior and eating efficiency in Duroc boars
    Ding, Rongrong
    Quan, Jianping
    Yang, Ming
    Wang, Xingwang
    Zheng, Enqin
    Yang, Huaqiang
    Fu, Disheng
    Yang, Yang
    Yang, Linxue
    Li, Zicong
    Liu, Dewu
    Cai, Gengyuan
    Wu, Zhenfang
    Yang, Jie
    PLOS ONE, 2017, 12 (08):
  • [4] Genome-wide association analysis reveals genetic loci and candidate genes for meat quality traits in Chinese Laiwu pigs
    Xiong, Xinwei
    Liu, Xianxian
    Zhou, Lisheng
    Yang, Jie
    Yang, Bin
    Ma, Huanban
    Xie, Xianhua
    Huang, Yixuan
    Fang, Shaoming
    Xiao, Shijun
    Ren, Jun
    Chen, Congying
    Ma, Junwu
    Huang, Lusheng
    MAMMALIAN GENOME, 2015, 26 (3-4) : 181 - 190
  • [5] Genome-wide association study reveals genetic loci and candidate genes for average daily gain in Duroc pigs
    Quan, Jianping
    Ding, Rongrong
    Wang, Xingwang
    Yang, Ming
    Yang, Yang
    Zheng, Enqin
    Gu, Ting
    Cai, Gengyuan
    Wu, Zhenfang
    Liu, Dewu
    Yang, Jie
    ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 2018, 31 (04): : 480 - 488
  • [6] Genome-Wide Association Study Reveals Novel Loci and Candidate Genes for Birth Weight in Pigs
    Liu, Jiajia
    Zeng, Yue
    Tian, Yu
    Cheng, Linghua
    Li, Wenchao
    Cheng, Shunfeng
    Wang, Junjie
    Li, Lan
    ANIMALS, 2025, 15 (06):
  • [7] Genome-Wide Association Analysis Reveals Genetic Loci and Candidate Genes for Chest, Abdominal, and Waist Circumferences in Two Duroc Pig Populations
    Zhou, Shenping
    Ding, Rongrong
    Zhuang, Zhanwei
    Zeng, Haiyu
    Wen, Shuxian
    Ruan, Donglin
    Wu, Jie
    Qiu, Yibin
    Zheng, Enqin
    Cai, Gengyuan
    Yang, Jie
    Wu, Zhenfang
    Yang, Ming
    FRONTIERS IN VETERINARY SCIENCE, 2022, 8
  • [8] Genome-wide association of volatiles reveals candidate loci for blueberry flavor
    Ferrao, Luis Felipe V.
    Johnson, Timothy S.
    Benevenuto, Juliana
    Edger, Patrick P.
    Colquhoun, Thomas A.
    Munoz, Patricio R.
    NEW PHYTOLOGIST, 2020, 226 (06) : 1725 - 1737
  • [9] Genome-wide association analysis of eggshell color of an F2 generation population reveals candidate genes in chickens
    Wang, X. G.
    Shen, M. M.
    Lu, J.
    Dou, T. C.
    Ma, M.
    Guo, J.
    Wang, K. H.
    Qu, L.
    ANIMAL, 2024, 18 (06)
  • [10] An approach based on a genome-wide association study reveals candidate loci for narcolepsy
    Shimada, Mihoko
    Miyagawa, Taku
    Kawashima, Minae
    Tanaka, Susumu
    Honda, Yutaka
    Honda, Makoto
    Tokunaga, Katsushi
    HUMAN GENETICS, 2010, 128 (04) : 433 - 441
12345