The Vaginal Virome in Women's Health and Disease

被引:0
|
作者
Orton, Kyra l'Cess [1 ,2 ]
Monaco, Cynthia L. [1 ,3 ]
机构
[1] Univ Rochester, Sch Med, Dept Microbiol & Immunol, Rochester, NY 14642 USA
[2] Michigan State Univ, Coll Human Med, E Lansing, MI 48824 USA
[3] Univ Rochester, Med Sch, Dept Med, Div Infect Dis, Rochester, NY 14642 USA
关键词
vaginal virome; female reproductive tract; bacteriome; vaginal microbiota transplant; bacterial vaginosis; BACTERIAL VAGINOSIS; LACTOBACILLUS PHAGES; VIRAL-INFECTION; HIV; ACQUISITION; MICROBIOTA; TRANSMISSION; INFLAMMATION; PREVALENCE;
D O I
10.3390/microorganisms13020431
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Most research on the vaginal microbiome has focused on bacterial communities (the bacteriome), but viruses, including eukaryotic viruses and bacteriophages, are also important players in vaginal health and disease states. In this review, we will briefly discuss the bacterial microbiome, delve into what is known about the vaginal virome and its impact on women's health, and finish with novel vaginal microbial or microbial-derived therapeutics on the horizon. More studies on the vaginal virome and its impact on women's health are needed to better prevent and treat gynecological, reproductive, and neonatal diseases.
引用
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页数:17
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