Cognitive Impairment and Insomnia in Celiac Disease: A Systematic Review and Meta-Analysis

被引：0

作者：

Beas, Renato ^{[1
]}

Godoy, Ambar ^{[1
]}

Norwood, Dalton A. ^{[2
]}

Ascencio, Ysaith Orellana ^{[3
]}

Izquierdo-Veraza, Diego ^{[1
]}

Montalvan-Sanchez, Eleazar E. ^{[1
]}

Ramirez, Mirian ^{[4
]}

Kurada, Satya ^{[5
]}

机构：

[1] Indiana Univ, Sch Med, Dept Med, Indianapolis, IN 46202 USA

[2] Univ Alabama Birmingham, Dept Med, Div Prevent Med, Birmingham, AL USA

[3] Ohio Univ, Heritage Coll Osteopath Med, Athens, OH USA

[4] Indiana Univ, Sch Med, Ruth Lilly Med Lib, Indianapolis, IN USA

[5] Indiana Univ, Sch Med, Div Gastroenterol & Hepatol, Indianapolis, IN USA

来源：

GUT AND LIVER | 2024年 / 18卷 / 06期

关键词：

Celiac disease; Insomnia; Cognitive impairment; GLUTEN-FREE DIET; SLEEP;

D O I：

10.5009/gnl240063

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Emerging evidence suggests a broader spectrum of celiac disease (CeD) system involvement, including neurological manifestations. We aimed to conduct a systematic review and meta-analysis of the available evidence from studies assessing the association of cognitive impairment and insomnia with CeD. A total of 259 participants with CeD were included in the studies investigating insomnia and 179 were included in studies investigating cognitive impairment. The overall pooled odds ratio for insomnia in patients with CeD was 1.83 (95% confidence interval, 1.38 to 2.42; I2=0.00%). The present study provides valuable insights into the available evidence from studies investigating cognitive impairment in patients with CeD and our systematic review and meta-analysis revealed a significant association between CeD and insomnia. (Gut Liver 2024;18:1080-1084)

引用

页码：1080 / 1084

页数：5

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