GPR56: GPCR as a guardian against ferroptosis

被引:0
|
作者
Yan, Yuelong [1 ]
Zhuang, Li [1 ]
Gan, Boyi [1 ,2 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Expt Radiat Oncol, Houston, TX 77030 USA
[2] Univ Texas MD Anderson, UTHealth Grad Sch Biomed Sci, Houston, TX 77030 USA
关键词
D O I
10.1016/j.cmet.2024.08.011
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Transmembrane receptor proteins are proficient in sensing external signals and initiating downstream pathways to control cell survival. Lin et al. demonstrated that GPR56, a G-protein-coupled receptor, can be activated by its agonist to suppress ferroptosis-a form of cell death-and effectively mitigate ferroptosis-associated liver damage.
引用
收藏
页码:2355 / 2356
页数:2
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