Effects of Mepolizumab in a Pediatric Population With Severe Asthma: Pharmacological Modeling, Simulation and Extrapolation of Data From Adult Patients

被引:0
|
作者
Phipatanakul, W. [1 ]
Gupta, A. [2 ,3 ]
Pouliquen, I. [4 ]
Austin, D. [4 ]
Whelan, G. [5 ]
Price, R. G. [6 ]
Finney-Hayward, T. [5 ]
Steinfeld, J. [7 ]
机构
[1] Harvard Med Sch, Boston Childrens Hosp, Div Allergy & Immunol, Dept Pediat, Boston, MA USA
[2] Kings Coll Hosp NHS Fdn Trust, Paediat Resp Med, London, England
[3] Kings Coll London, London, England
[4] GSK, Clin Pharmacol Modelling & Simulat, Uxbridge, Middx, England
[5] GSK, Global Med Affairs, London, England
[6] GSK, Biostat, Stevenage, Herts, England
[7] Areteia Therapeut, Clin Dev, Chapel Hill, NC USA
关键词
D O I
暂无
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A6702
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Mepolizumab prefilled syringe for the treatment of severe eosinophilic asthma: focus on the pediatric population
    Revier, Michelle Dilley
    Geng, Bob
    EXPERT REVIEW OF RESPIRATORY MEDICINE, 2022, 16 (08) : 857 - 865
  • [2] Mepolizumab in Pediatric Patients with Severe Eosinophilic Asthma: A Single Center Experience
    Rotolo, S. M.
    Hegde, S.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2019, 199
  • [3] Mepolizumab Treatment in Severe Pediatric Asthma: First Multicentric Real-World Data
    Wetzke, Martin
    Funken, Dominik
    Ahrens, Frank O.
    Gappa, Monika
    Hansen, Gesine
    Koerner-Rettberg, Cordula
    Koester, Holger
    Schulze, Johannes
    Schwerk, Nicolaus
    Zielen, Stefan
    Happle, Christine
    KLINISCHE PADIATRIE, 2022, 234 (05): : 305 - 308
  • [4] ORAL CORTICOSTEROID EXPOSURE IN PATIENTS WITH SEVERE EOSINOPHILIC ASTHMA: DATA FROM THE AUSTRALIAN MEPOLIZUMAB REGISTRY
    Thomas, D.
    Harvey, E.
    Stevens, S.
    McDonald, V
    Simpson, J.
    Upham, J.
    Katelaris, C.
    Harrington, J.
    Gibson, P.
    RESPIROLOGY, 2020, 25 : 124 - 124
  • [5] Real life data on treatment response to mepolizumab in patients with severe eosinophilic asthma
    Ntakoula, M.
    Fokoloros, C.
    Pasali, M.
    Aggelides, X.
    Makris, M.
    ALLERGY, 2019, 74 : 446 - 446
  • [6] Real-World Impact of Mepolizumab on Pediatric and Adolescent Patients With Severe Asthma in the United States
    Corbridge, T.
    Mahendran, M.
    Hilts, A.
    Zhang, K.
    Laliberte, F.
    Deb, A.
    AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2024, 209
  • [7] TRANSFER OF PATIENTS FROM MEPOLIZUMAB TO BENRALIZUMAB: EXPERIENCE IN A BIOLOGIC CLINIC FOR SEVERE ASTHMA
    Thompson, P.
    Banders, N.
    Keogh, L.
    Dina, S.
    Nye, B.
    Store, L.
    Stevens, M.
    Thompson, G.
    RESPIROLOGY, 2020, 25 : 106 - 106
  • [8] Impact of mepolizumab in patients with high-burden severe asthma within a managed care population
    Lugogo, Njira L.
    Bogart, Michael
    Corbridge, Thomas
    Packnett, Elizabeth R.
    Wu, Joanne
    Hahn, Beth
    JOURNAL OF ASTHMA, 2023, 60 (04) : 811 - 823
  • [9] ANALYSIS OF CLINICAL EFFECTS OF MEPOLIZUMAB IN PATIENTS WITH SEVERE EOSINOPHILIC ASTHMA: A SINGLE INSTITUTIONAL STUDY
    Yamaguchi, Masafumi
    Nakagawa, Hiroaki
    Kinose, Daisuke
    Nagao, Taishi
    Ogawa, Emiko
    Nakano, Yasutaka
    RESPIROLOGY, 2019, 24 : 196 - 196
  • [10] Severe Asthma-Perspectives From Adult and Pediatric Pulmonology
    Fleming, Louise
    Heaney, Liam
    FRONTIERS IN PEDIATRICS, 2019, 7