Humanized mouse models for the preclinical evaluation of novel immune cell therapies, check point inhibitors, and immune cell engagers

被引：0
|
作者：
Stecklum, Maria [1 ]
Wulf-Goldenberg, Annika [1 ]
Alcaniz, Joshua [1 ]
Brzezicha, Bernadette [1 ]
Wolfgang, Walther [1 ,2 ]
Hoffmann, Jens [1 ]
机构：
[1] EPO GmbH, Berlin, Germany
[2] Charite Univ Med Berlin, ECRC, Berlin, Germany
来源：
ONCOLOGY RESEARCH AND TREATMENT | 2024年 / 47卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
600
引用
收藏
页码：222 / 223
页数：2
相关论文
共 50 条
  • [1] Preclinical evaluation of novel immune cell therapies, check point inhibitors, and immune cell engagers in humanized mouse models
    Stecklum, Maria
    Wulf-Goldenberg, Annika
    Brzezicha, Bernadette
    Alcaniz, Joshua
    Smits, Glenn
    Walther, Wolfgang
    Hoffmann, Jens
    MOLECULAR CANCER THERAPEUTICS, 2023, 22 (12)
  • [2] Humanized mouse models for preclinical evaluation of novel immune cell therapies, checkpoint inhibitors, and immune cell engagers
    Stecklum, Maria
    Wulf-Goldenberg, Annika
    Brzezicha, Bernadette
    Walther, Wolfgang
    Hoffmann, Jens
    CANCER RESEARCH, 2022, 82 (12)
  • [3] Humanized mouse models for preclinical evaluation of novel immune therapies, checkpoint inhibitors and immune cell engagers
    Stecklum, M.
    Brzezicha, B.
    Rhein, S.
    Walther, W.
    Hoffmann, J.
    EUROPEAN JOURNAL OF CANCER, 2022, 174 : S12 - S12
  • [4] GENERATION OF HUMANIZED MOUSE MODELS FOR THE PRECLINICAL EVALUATION OF NOVEL IMMUNE CHECKPOINT INHIBITORS, IMMUNE CELL ENGAGERS AND CELL THERAPIES
    Stecklum, Maria
    Wulf-Goldenberg, Annika
    Brzezicha, Bernadette
    Rupp, Christian
    Walther, Wolfgang
    Hoffmann, Jens
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A167 - A167
  • [5] Novel in vivo preclinical humanized models for the evaluation of human specific immune checkpoint inhibitors
    Avrutskaya, Anya
    Sonego, Fabienne
    Hauser, Jacob
    O'Koren, Emily
    Ball, Robin
    Martin, Gaelle
    Chaix, Julie
    Thi Bui
    Belle, Ian
    Reap, Elizabeth
    Fadden, Patrick
    Hall, Chassidy
    Thiam, Kader
    de Marval, Paula Miliani
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7
  • [6] Humanization of NOG mice and next-generation NOG strains to induce lineage-specific differentiation of immune cells for assessment of novel immune cell therapies, check point inhibitors, and immune cell engagers for translational immunooncology research
    Stecklum, Maria
    Baskin, Louise
    Hoffmann, Jens
    CANCER RESEARCH, 2024, 84 (06)
  • [7] Kidney Immune Cell Characterization of Humanized Mouse Models
    Noel, Sanjeev
    Kurzhagen, Johanna T.
    Lee, Sul A.
    Sadasivam, Mohanraj
    Hamad, Abdel R. A.
    Pierorazio, Phillip M.
    Rabb, Hamid
    KIDNEY360, 2024, 5 (01): : 96 - 109
  • [8] HUMANIZED MOUSE MODELS FOR PRECLINICAL TESTING OF ANTITUMOUR IMMUNE THERAPY
    Annika, Wulf-Goldenberg
    Maria, Stecklum
    Iduna, Fichtner
    Jens, Hoffmann
    EUROPEAN JOURNAL OF CANCER, 2015, 51 : S2 - S2
  • [9] Donor selection strategies to optimize humanized mouse models for the evaluation of T cell engagers.
    Cheng, Liqing
    Chen, Jane
    Yu, Qunyan
    Malkova, Natalia
    Cortez-Retamozo, Virna F.
    Sun, Fangxian
    Sidhu, Sukhvinder
    CANCER RESEARCH, 2021, 81 (13)
  • [10] CD3 HUMANIZED MOUSE MODELS AS VALIDATED TOOLS TO ASSESS IMMUNE-RELATED ADVERSE EVENTS OF T CELL ENGAGERS
    Martin-Jeantet, Perrine
    Martin, Gaelle
    Pappalardo, Angela
    Renart-depontieu, Florence
    Isnard-Petit, Patricia
    Cherifi, Yacine
    Sonego, Fabiane
    Thiam, Kader
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A157 - A157
12345