Thrombospondin-1 induces immunogenic cell death in human mucoepidermoid carcinoma MC-3 cells via the PERK/eIF2α signaling pathway: potential implications for tumor immunotherapy

被引:0
|
作者
Yixuan Zhu [1 ]
Kaizhi Cai [2 ]
Lijuan Guo [2 ]
Huan Zhang [2 ]
Li Guan [2 ]
Zongyao Zhang [2 ]
Pengcheng Huang [3 ]
Sen Yang [2 ]
机构
[1] North Sichuan Medical College,Department of Oral and Maxillofacial Surgery
[2] Suining Central Hospital,Department of General Surgery
[3] The First Affiliated Hospital of Anhui University of Science and Technology,undefined
关键词
Thrombospondin-1; MC-3 cell line; Immunogenic death; Calreticulin; PERK/eIF2α signaling pathway; Tumor immunotherapy;
D O I
10.1007/s12672-025-02315-7
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 6 条
  • [1] Sorafenib induces autophagic cell death and apoptosis in hepatoma HepG2 cells via PERK/EIF2α signaling pathway
    Liu, Ze-feng
    Liu, Qi-Lin
    Li, Fu-Jian
    Yang, Zhou-Fan
    Chen, Li
    Zhang, Guo
    FASEB JOURNAL, 2019, 33
  • [2] Huaier Induces Immunogenic Cell Death Via CircCLASP1/PKR/eIF2α Signaling Pathway in Triple Negative Breast Cancer
    Li, Chen
    Wang, Xiaolong
    Chen, Tong
    Li, Wenhao
    Zhou, Xianyong
    Wang, Lishui
    Yang, Qifeng
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 10
  • [3] Melatonin Induces AGS Gastric Cancer Cell Apoptosis via Regulating PERK/eIF2α and HSF1/NF-κB Signaling Pathway
    Li, Weimin
    Hu, Chengchen
    Zhong, Xueqing
    Wu, Jianliang
    Li, Guodong
    ANNALS OF CLINICAL AND LABORATORY SCIENCE, 2022, 52 (01): : 40 - 47
  • [4] 7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway
    Tsai, Tsung-Chang
    Lai, Kuei-Hung
    Su, Jui-Hsin
    Wu, Yu-Jen
    Sheu, Jyh-Horng
    MARINE DRUGS, 2018, 16 (04):
  • [5] Dehydrocostus Lactone Induces Apoptosis and Cell Cycle Arrest through Regulation of JAK2/STAT3/PLK1 Signaling Pathway in Human Esophageal Squamous Cell Carcinoma Cells
    Yang, Ganghua
    Sheng, Binwu
    Li, Ruixiang
    Xu, Qinhong
    Zhang, Lei
    Lu, Zhengyang
    ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2022, 22 (09) : 1742 - 1752
  • [6] Curcumol induces cell cycle arrest and apoptosis by inhibiting IGF-1R/PI3K/Akt signaling pathway in human nasopharyngeal carcinoma CNE-2 cells
    Li, Xumei
    Liu, Haowei
    Wang, Juan
    Qin, Jianli
    Bai, Zhun
    Chi, Bixia
    Yan, Wei
    Chen, Xu
    PHYTOTHERAPY RESEARCH, 2018, 32 (11) : 2214 - 2225