Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS

被引：0
|
作者：
Wodzanowski, Kimberly [2 ]
Akuma, Daniel [1 ]
Wertman, Ronit Schwartz [1 ]
Exconde, Patrick [2 ]
Marrero, Victor Vazquez [2 ]
Odunze, Chukwuma [3 ]
Grubaugh, Daniel [1 ]
Shin, Sunny [2 ]
Taabazuing, Cornelius [2 ]
Brodsky, Igor [1 ]
机构：
[1] Univ Penn, Sch Vet Med, Philadelphia, PA USA
[2] Univ Penn, Perelman Sch Med, Philadelphia, PA USA
[3] Univ Maryland, College Pk, MD USA
来源：
JOURNAL OF IMMUNOLOGY | 2024年 / 212卷 / 01期
关键词：
D O I：
10.4049/jimmunol.212.supp.1128.5912
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页数：2
相关论文
共 20 条
  • [1] Catalytic activity and autoprocessing of murine caspase-11 mediate noncanonical inflammasome assembly in response to cytosolic LPS
    Akuma, Daniel C.
    Wodzanowski, Kimberly A.
    Wertman, Ronit Schwartz
    Exconde, Patrick M.
    Marrero, Victor R. Vazquez
    Odunze, Chukwuma E.
    Grubaugh, Daniel
    Shin, Sunny
    Taabazuing, Cornelius
    Brodsky, Igor E.
    ELIFE, 2024, 13
  • [2] Caspase-11: The Noncanonical Guardian of Cytosolic Sanctity
    Shin, Sunny
    Brodsky, Igor E.
    CELL HOST & MICROBE, 2013, 13 (03) : 243 - 245
  • [3] Bacterial Outer Membrane Vesicles Mediate Cytosolic Localization of LPS and Caspase-11 Activation
    Vanaja, Sivapriya Kailasan
    Russo, Ashley J.
    Behl, Bharat
    Banerjee, Ishita
    Yankova, Maya
    Deshmukh, Sachin D.
    Rathinam, Vijay A. K.
    CELL, 2016, 165 (05) : 1106 - 1119
  • [4] Caspase-11 Noncanonical Inflammasome: A Novel Key Player in Murine Models of Neuroinflammation and Multiple Sclerosis
    Yi, Young-Su
    NEUROIMMUNOMODULATION, 2021, 28 (04) : 195 - 203
  • [5] Caspase-11 auto-proteolysis is crucial for noncanonical inflammasome activation
    Lee, Bettina L.
    Stowe, Irma B.
    Gupta, Aaron
    Kornfeld, Opher S.
    Roose-Girma, Merone
    Anderson, Keith
    Warming, Soren
    Zhang, Juan
    Lee, Wyne P.
    Kayagaki, Nobuhiko
    JOURNAL OF EXPERIMENTAL MEDICINE, 2018, 215 (09): : 2279 - 2288
  • [6] Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
    Brice Lagrange
    Sacha Benaoudia
    Pierre Wallet
    Flora Magnotti
    Angelina Provost
    Fanny Michal
    Amandine Martin
    Flaviana Di Lorenzo
    Bénédicte F. Py
    Antonio Molinaro
    Thomas Henry
    Nature Communications, 9
  • [7] Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
    Lagrange, Brice
    Benaoudia, Sacha
    Wallet, Pierre
    Magnotti, Flora
    Provost, Angelina
    Michal, Fanny
    Martin, Amandine
    Di Lorenzo, Flaviana
    Py, Benedicte F.
    Molinaro, Antonio
    Henry, Thomas
    NATURE COMMUNICATIONS, 2018, 9
  • [8] Non-canonical inflammasome activation of Caspase-11 protects against cytosolic bacteria
    Aachoui, Youssef
    Leaf, Irina
    Hagar, Jon
    Fontana, Mary
    Campos, Cristine
    Zak, Daniel
    Tan, Michael
    Cotter, Peggy
    Vance, Russell
    Aderem, Alan
    Miao, Edward
    JOURNAL OF IMMUNOLOGY, 2013, 190
  • [9] Quercetin Ameliorates Acute Lethal Sepsis in Mice by Inhibiting Caspase-11 Noncanonical Inflammasome in Macrophages
    Kim, Eojin
    Choi, Deok-Hyeong
    Yi, Young-Su
    MOLECULES, 2024, 29 (24):
  • [10] Noncanonical Inflammasome Activation of Caspase-4/Caspase-11 Mediates Epithelial Defenses against Enteric Bacterial Pathogens
    Knodler, Leigh A.
    Crowley, Shauna M.
    Sham, Ho Pan
    Yang, Hyungjun
    Wrande, Marie
    Ma, Caixia
    Ernst, Robert K.
    Steele-Mortimer, Olivia
    Celli, Jean
    Vallance, Bruce A.
    CELL HOST & MICROBE, 2014, 16 (02) : 249 - 256
12