The friction and wear behavior of cold-work tool steel materials is a subject of interest to researchers and tribologists. Both friction and wear are the key factors affecting the life of a tool. This study investigates the abrasive wear performance of Vanadis 6 material against the sintered alumina (Al2O3) counterpart. The friction and wear tests were performed on a pin on disk tribometer at room temperature. The design of experiment approach based on the Taguchi methodology was used for experimentation and Taguchi's L18 orthogonal array was used based on the mixed levels (2(<^>)1 3(<^>)3) of the control factors viz., tempering temperature, subzero temperature, sliding velocity, and load. Further, the ANOVA technique was used to identify the significant factors and their contribution to the tribological performance of Vanadis 6. It is evident that the load is the most significant parameter that affects both the mean friction coefficient and wear rate followed by tempering temperature. Taguchi analysis revealed that using a tempering temperature of 170C degrees, the subzero temperature of -140 degrees C, the sliding velocity of 18.85 cm/s, and 10N normal load gives the optimum setting for the mean coefficient of friction and a tempering temperature of 170C degrees, sub-zero temperature of -140 degrees C, sliding velocity of 6.4 cm/s, and 1N normal load gives the optimum setting for wear rate.