The reactivity of cysteines of 3CLpro affects the oligomerization state of the Sars-CoV-2 protease

被引：0
|
作者：
Cipollone, I. [1 ]
Iacobucci, I. [1 ]
Cozzolino, F. [1 ]
Morasso, S. [2 ]
Storici, P. [2 ]
Iaconis, D. [3 ]
Talarico, C. [3 ]
Manelfi, C. [4 ]
Beccari, A. [3 ]
Monti, M. [1 ]
机构：
[1] Univ Naples Federico II, Naples, Italy
[2] Elettra Sincrotrone Trieste, Trieste, Italy
[3] Dompe Farmaceut SpA, Naples, Italy
[4] Dompe Farmaceut SpA, Laquila, Italy
来源：
FEBS OPEN BIO | 2024年 / 14卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
P-34-024
引用
收藏
页码：422 / 422
页数：1
相关论文
共 50 条
  • [1] Discovery of 3CLpro inhibitor of SARS-CoV-2 main protease
    Kuang, Yi
    Ma, Xiaodong
    Shen, Wenjing
    Rao, Qingqing
    Yang, Shengxiang
    FUTURE SCIENCE OA, 2023, 9 (04):
  • [2] Inhibition of the SARS-CoV-2 3CLpro main protease by plant polyphenols
    Bahun, Miha
    Jukic, Marko
    Oblak, Domen
    Kranjc, Luka
    Bajc, Gregor
    Butala, Matej
    Bozovicar, Kristof
    Bratkovic, Tomaz
    Podlipnik, Crtomir
    Ulrih, Natasa Poklar
    FOOD CHEMISTRY, 2022, 373
  • [3] Repurposing of HIV/HCV protease inhibitors against SARS-CoV-2 3CLpro
    Ma, Ling
    Li, Quanjie
    Xie, Yongli
    Zhao, Jianyuan
    Yi, Dongrong
    Guo, Saisai
    Guo, Fei
    Wang, Jing
    Yang, Long
    Cen, Shan
    ANTIVIRAL RESEARCH, 2022, 207
  • [4] Geraniin as a potential inhibitor of SARS-CoV-2 3CLpro
    Yu, Wen-Di
    Jin, Qi-Ying
    Zeng, Mao-Sen
    Liu, Jin-Yuan
    Xu, Pei-Ping
    NATURAL PRODUCT RESEARCH, 2022, 36 (23) : 6060 - 6063
  • [5] Protocol for production and purification of SARS-CoV-2 3CLpro
    Mazzei, Luca
    Greene-Cramer, Rebecca
    Bafna, Khushboo
    Jovanovic, Aleksandar
    De Falco, Anna
    Acton, Thomas B.
    Royer, Catherine Ann
    Ciurli, Stefano
    Montelione, Gaetano T.
    STAR PROTOCOLS, 2023, 4 (02):
  • [6] Sensitive detection of SARS-CoV-2 main protease 3CLpro with an engineered ribonuclease zymogen
    Wralstad, Evans C.
    Raines, Ronald T.
    PROTEIN SCIENCE, 2024, 33 (04)
  • [7] The main protease 3CLpro of the SARS-CoV-2 virus: how to turn an enemy into a helper
    Belenkaya, Svetlana V.
    Merkuleva, Iuliia A.
    Yarovaya, Olga I.
    Chirkova, Varvara Yu.
    Sharlaeva, Elena A.
    Shanshin, Daniil V.
    Volosnikova, Ekaterina A.
    Vatsadze, Sergey Z.
    Khvostov, Mikhail V.
    Salakhutdinov, Nariman F.
    Shcherbakov, Dmitriy N.
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 11
  • [8] Bayesian Inference Elucidates the Catalytic Competency of the SARS-CoV-2 Main Protease 3CLpro
    Wralstad, Evans C.
    Sayers, Jessica
    Raines, Ronald T.
    ANALYTICAL CHEMISTRY, 2023, 95 (40) : 14981 - 14989
  • [9] A Study of Drug Repurposing to Identify SARS-CoV-2 Main Protease (3CLpro) Inhibitors
    Jo, Seri
    Signorile, Luca
    Kim, Suwon
    Kim, Mi-Sun
    Huertas, Oscar
    Insa, Raul
    Reig, Nuria
    Shin, Dong Hae
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 23 (12)
  • [10] Cys44 of SARS-CoV-2 3CLpro affects its catalytic activity
    Iacobucci, Ilaria
    Cipollone, Irene
    Cozzolino, Flora
    Iaconis, Daniela
    Talarico, Carmine
    Coppola, Gabriele
    Morasso, Stefano
    Costanzi, Elisa
    Malune, Paolo
    Storici, Paola
    Tramontano, Enzo
    Esposito, Francesca
    Monti, Maria
    INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 295
12345