Predictive biomarkers of performance under stress: a two-phase study protocol to develop a wearable monitoring system

被引:0
|
作者
Flintoff, Jonathan M. [1 ,2 ]
Pattinson, Cassandra [3 ]
Ahamed, Sarah [4 ]
Ali, Shahnewaz [5 ]
Bagley, Angus [1 ,2 ]
Broszczak, Daniel [1 ,2 ]
Crewther, Blair [5 ,6 ]
de Waal, Louis [3 ,7 ]
Edmed, Shannon L. [3 ]
Fernando, Tharindu [5 ]
Fookes, Clinton [2 ,5 ]
Frentiu, Francesca D. [1 ,8 ]
Hunt, Andrew P. [1 ,2 ]
Lipp, Ottmar, V [4 ]
Mcmaster, Ben [9 ]
Mengersen, Kerrie [10 ,11 ]
Ney, Luke [4 ]
Oon, Senn L. [1 ,2 ]
Pandey, Ajay [2 ,5 ]
Pandit, Parth [5 ]
Peake, Jonathan M. [1 ,2 ]
Perera, Muthukuttige Madusha Nuwanthi [1 ,2 ]
Perlo, Virginie [1 ,2 ]
Punyadeera, Chamindie [12 ]
Schmidt, Luke [1 ,2 ]
Smith, Simon S. [3 ]
Spann, Kirsten [1 ,8 ]
Stewart, Ian [9 ]
Sullivan, Karen A. [4 ]
Young, Danielle [1 ,2 ]
Kerr, Graham [2 ,9 ]
Parker, Tony J. [1 ,2 ]
机构
[1] Queensland Univ Technol, Sch Biomed Sci, Brisbane, Qld, Australia
[2] Queensland Univ Technol, Ctr Biomed Technol, Brisbane, Qld, Australia
[3] Univ Queensland, Child Hlth Res Ctr, Brisbane, Qld, Australia
[4] Queensland Univ Technol, Sch Psychol & Counselling, Brisbane, Qld, Australia
[5] Queensland Univ Technol, Sch Elect Engn & Robot, Brisbane, Qld, Australia
[6] Univ New England, Sch Sci & Technol, Armidale, NSW, Australia
[7] Univ Queensland, Ctr Res Excellence Stillbirth, Mater Res, Brisbane, Qld, Australia
[8] Queensland Univ Technol, Ctr Immunol & Infect Control, Brisbane, Qld, Australia
[9] Queensland Univ Technol, Sch Exercise & Nutr Sci, Brisbane, Qld, Australia
[10] Queensland Univ Technol, Ctr Data Sci, Brisbane, Qld, Australia
[11] Queensland Univ Technol, Sch Math Sci, Brisbane, Qld, Australia
[12] Griffith Univ, Inst Glycom, Brisbane, Qld, Australia
来源
BMJ OPEN SPORT & EXERCISE MEDICINE | 2025年 / 11卷 / 01期
关键词
Stress; Performance; Biochemistry; HEAT-STRESS; SLEEP; RECOMMENDATIONS; RESPONSES; INJURIES; FATIGUE; COLD; TASK;
D O I
10.1136/bmjsem-2024-002410
中图分类号
G8 [体育];
学科分类号
04 ; 0403 ;
摘要
Understanding and predicting individual responses to common stressors is essential for optimising performance in high-stress environments. This article outlines a protocol for a study to identify biomarkers that predict performance under heat, musculoskeletal, psychosocial and sleep stress, for future integration into a wearable sensor system. In Phase I, healthy adults aged between 18 and 45 years (n=104) will be recruited for an intervention trial that involves exposure to one of the four stressors: heat, musculoskeletal, psychosocial or sleep deprivation. Biomarkers will be identified from molecular markers in biological samples (eg, blood, saliva, sweat and stool), physiological measures and psychological assessments to predict cognitive and physical performance under stress. A within-subjects design will determine changes in molecular and non-molecular markers before and after stress exposure. In Phase II, we will use the biomarkers identified in Phase I to develop a wearable sensor to predict and monitor human performance under stress.
引用
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页数:10
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