The heterogeneity of urothelial carcinoma (UC) and variable treatment responses poses significant clinical challenges. In this issue of Cancer Cell, Hamidi et al. conducted a multi-omics analysis of 2,803 UC patients from four clinical trials with anti-PD-L1, revealing four transcriptional subtypes. This approach could help tailor therapies for UC.
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Boston Childrens Hosp, Dept Urol, Boston, MA USA
Harvard Univ, Sch Med, Dept Surg, Boston, MA 02115 USABoston Childrens Hosp, Dept Urol, Boston, MA USA
Adam, Rosalyn M.
DeGraff, David J.
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Penn State Univ, Coll Med, Dept Pathol, Hershey, PA 17033 USA
Penn State Univ, Coll Med, Dept Biochem & Mol Biol, Hershey, PA USA
Penn State Univ, Coll Med, Div Urol, Dept Surg, Hershey, PA USABoston Childrens Hosp, Dept Urol, Boston, MA USA
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Clin Res & Pract Ctr Specialized Oncol Care, St Petersburg, Russia
St Petersburg Medicosocial Inst, St Petersburg, RussiaClin Res & Pract Ctr Specialized Oncol Care, St Petersburg, Russia
Shelekhova, Ksenya V.
Krykow, Kirill A.
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Clin Res & Pract Ctr Specialized Oncol Care, St Petersburg, RussiaClin Res & Pract Ctr Specialized Oncol Care, St Petersburg, Russia
Krykow, Kirill A.
Mescherjakov, Igor A.
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Clin Res & Pract Ctr Specialized Oncol Care, St Petersburg, RussiaClin Res & Pract Ctr Specialized Oncol Care, St Petersburg, Russia
Mescherjakov, Igor A.
Mitin, Nikolay P.
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Clin Res & Pract Ctr Specialized Oncol Care, St Petersburg, RussiaClin Res & Pract Ctr Specialized Oncol Care, St Petersburg, Russia
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Univ N Carolina, Sch Med, Chapel Hill, NC USAUniv N Carolina, Sch Med, Chapel Hill, NC USA
Weiss, Kristin
Gessner, Kathryn H.
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Univ N Carolina, Dept Urol, Chapel Hill, NC USAUniv N Carolina, Sch Med, Chapel Hill, NC USA
Gessner, Kathryn H.
Demzik, Alysen
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Univ N Carolina, Dept Urol, Chapel Hill, NC USAUniv N Carolina, Sch Med, Chapel Hill, NC USA
Demzik, Alysen
Moreton, Elizabeth
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Univ North Carolina Lib Syst, Chapel Hill, NC USAUniv N Carolina, Sch Med, Chapel Hill, NC USA
Moreton, Elizabeth
Kim, William Y.
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Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA
Univ N Carolina, Dept Pharmacol, Chapel Hill, NC USA
Univ N Carolina, Dept Med, Div Hematol Oncol, Chapel Hill, NC USA
Univ N Carolina, Dept Genet, Chapel Hill, NC USAUniv N Carolina, Sch Med, Chapel Hill, NC USA
Kim, William Y.
Wobker, Sara E.
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Univ N Carolina, Dept Urol, Chapel Hill, NC USA
Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA
Univ N Carolina, Dept Pathol & Lab Med, Chapel Hill, NC USAUniv N Carolina, Sch Med, Chapel Hill, NC USA
Wobker, Sara E.
Rose, Tracy L.
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Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA
Univ N Carolina, Dept Med, Div Hematol Oncol, Chapel Hill, NC USAUniv N Carolina, Sch Med, Chapel Hill, NC USA
Rose, Tracy L.
Milowsky, Matthew I.
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Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA
Univ N Carolina, Dept Med, Div Hematol Oncol, Chapel Hill, NC USAUniv N Carolina, Sch Med, Chapel Hill, NC USA
Milowsky, Matthew I.
Bjurlin, Marc A.
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Univ N Carolina, Dept Urol, Chapel Hill, NC USA
Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USAUniv N Carolina, Sch Med, Chapel Hill, NC USA