A phase I, open-label, multicenter, dose escalation safety and tolerability study of oncolytic virus OVV-01 in advanced solid tumors

被引:0
|
作者
Hua, Y. [1 ,9 ]
Wang, C. [1 ,9 ]
Li, F. [2 ]
Han, Y. [3 ]
Zuo, D. [1 ,9 ]
Lv, Y. [1 ,9 ]
Peng, Y. [4 ]
Chen, J. [5 ,6 ]
Yuan, R. [7 ]
Zhang, F. [8 ]
Wang, Y. [10 ]
Wu, H. [10 ]
Zhou, G. [10 ]
Wang, S. [3 ]
Li, N. [3 ]
Lu, Y. [11 ]
Lin, Q. [12 ]
机构
[1] Shanghai Jiao Tong Univ, Dept Orthoped, Peoples Hosp 1, Shanghai Gen Hosp, Shanghai, Peoples R China
[2] Beijing GoBroad Boren Hosp, Dept Hepatobiliary Oncol, GoBroad Med Hematol, Beijing Res Ctr, Beijing, Peoples R China
[3] Chinese Acad Med Sci, Peking Union Med Coll, Natl Canc Ctr, Clin Trial Ctr,Natl Clin Res Ctr Canc,Canc Hosp, Beijing, Peoples R China
[4] Chinese Acad Med Sci & Peking Union Med Coll, Canc Hosp, Dept VIP Med Serv, Natl Canc Ctr, Beijing, Peoples R China
[5] MIT, Koch Inst Integrat Canc Res, 77 Massachusetts Ave, Cambridge, MA 02139 USA
[6] MIT, Dept Biol, 77 Massachusetts Ave, Cambridge, MA 02139 USA
[7] Dowlin Biomed, Dept Immunotherapy, Hooksett, NH USA
[8] Dept Immunol, Hillsboro, OR USA
[9] Shanghai Jiao Tong Univ, Shanghai Bone Tumor Inst, Shanghai Gen Hosp, Dept Orthoped Oncol,Sch Med, Shanghai, Peoples R China
[10] Joint Biosci SH Ltd, Shanghai, Peoples R China
[11] Peking Univ, Dept Hepatobiliary Oncol, Med Ctr 302, Hlth Sci Ctr, Beijing, Peoples R China
[12] Hebei Med Univ, Dept Oncol, North China Petr Bur Gen Hosp, Shijiazhuang, Hebei, Peoples R China
关键词
D O I
10.1016/j.annonc.2024.08.1052
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
993MO
引用
收藏
页码:S677 / S677
页数:1
相关论文
共 50 条
  • [1] A phase I, open-label, multicenter dose escalation study to assess the safety, tolerability, and pharmacokinetics of AZD2811 nanoparticle in patients with advanced solid tumors.
    Johnson, Melissa Lynne
    Wang, Judy Sing-Zan
    Falchook, Gerald Steven
    Charlton, Julie
    MacDonald, Alexander
    Strickland, Donald
    Jones, Suzanne Fields
    Pease, Elizabeth J.
    Brugger, Wolfram
    Burris, Howard A.
    JOURNAL OF CLINICAL ONCOLOGY, 2018, 36 (15)
  • [2] Phase I, multicenter, open-label, dose-escalation study of sonidegib in Asian patients with advanced solid tumors
    Minami, Hironobu
    Ando, Yuichi
    Ma, Brigette Buig Yue
    Lee, Jih-Hsiang
    Momota, Hiroyuki
    Fujiwara, Yutaka
    Li, Leung
    Fukino, Koichi
    Ito, Koji
    Tajima, Takeshi
    Mori, Asuka
    Lin, Chia-Chi
    CANCER SCIENCE, 2016, 107 (10) : 1477 - 1483
  • [3] A phase 1, open-label, dose escalation study on the safety and tolerability of ANK-101 in advanced solid tumors.
    Park, Jong Chul
    Butler, Marcus O.
    Curti, Brendan D.
    Emens, Leisha A.
    Pastor, Danielle M.
    Elassal, Joseph
    Kaufman, Howard L.
    Kirkwood, John M.
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [4] Phase I, open-label, dose-escalation trial investigating the safety and efficacy of oncolytic virus BI 1821736 in patients with advanced solid tumors.
    Tolcher, Anthony W.
    Victoria, Ivan
    Germann, Nathalie
    Luecke, Stephan
    Bailey, Mark
    Kordes, Maximilian
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (16)
  • [5] Open-Label, Multicenter, Phase I Study to Assess Safety and Tolerability of Adavosertib Plus Durvalumab in Patients with Advanced Solid Tumors
    Patel, Manish R.
    Falchook, Gerald S.
    Wang, Judy S.
    Imedio, Esteban Rodrigo
    Kumar, Sanjeev
    Miah, Kowser
    Mugundu, Ganesh M.
    Jones, Suzanne F.
    Spigel, David R.
    Hamilton, Erika P.
    TARGETED ONCOLOGY, 2025, 20 (01) : 127 - 138
  • [6] Open-label, multicenter, phase I study to assess safety and tolerability of adavosertib plus durvalumab in patients with advanced solid tumors.
    Patel, Manish R.
    Falchook, Gerald Steven
    Wang, Judy Sing-Zan
    Imedio, Esteban Rodrigo
    Kumar, Sanjeev
    Motlagh, Pejvack
    Miah, Kowser
    Mugundu, Ganesh M.
    Jones, Suzanne Fields
    Spigel, David R.
    Hamilton, Erika Paige
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [7] A PHASE 1/2, OPEN-LABEL, DOSE-ESCALATION, SAFETY AND TOLERABILITY STUDY OF NC762 IN SUBJECTS WITH ADVANCED OR METASTATIC SOLID TUMORS
    Myint, Han
    Shah, Satish
    Gutierrez, Martin
    Zsiros, Emese
    Nelson, Megan
    Zeidan, Stephanie
    Myrthil, Nadia
    Morawski, Aaron
    Barbu, Alina
    Shaik, Jahangheer
    Zhou, Chelsea
    Kanellopoulou, Chrysi
    Copeland, Ron
    Cusumano, Zachary
    Flies, Dallas
    Langermann, Solomon
    Lorusso, Patricia
    Odunsi, Kunle
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A781 - A781
  • [8] Trial in progress: A phase I/II, open-label, dose-escalation, safety and tolerability study of NC318 in subjects with advanced or metastatic solid tumors.
    Gutierrez, Martin
    Hamid, Omid
    Shum, Elaine
    Wise, David R.
    Balar, Arjun Vasant
    Weber, Jeffrey S.
    LoRusso, Patricia
    Shafi, Saba
    Rimm, David L.
    Tolcher, Anthony W.
    Basudhar, Debashree
    Dujka, Melanie Elizabeth
    Heller, Kevin N.
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [9] A phase 1/2, open-label, dose-escalation, safety and tolerability study of NC410 in subjects with advanced or metastatic solid tumors.
    Gutierrez, Martin
    Janku, Filip
    Tian, Linjie
    Luke, Jason J.
    Shum, Elaine
    Shin, John
    Weiss, Ido
    Liu, Linda N.
    Files, Dallas
    Langermann, Solomon
    Myint, Han
    Bilusic, Marijo
    JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
  • [10] A phase I/IIa, open-label, dose-escalation and expansion study to investigate the safety, tolerability, pharmacokinetics and pharmacodynamics of TJ107 in Chinese patients with advanced solid tumors
    Li, Jin
    Guo, Ye
    Peng, Wei
    Xue, Junli
    Zhao, Wei
    Ge, Xiaoxiao
    Xue, Liqiong
    Tang, Wenbo
    Zhou, Li
    Zhang, Min
    Guo, Bingshi
    Wang, Liping
    Guo, Jiyuan
    Cui, Feifei
    Suo, Haiyun
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2019, 7