Frequency of cutaneous drug reactions in the outpatient dermatology clinic at the National Institute of Cardiology Ignacio Chávez over a ten-year period

被引：0

作者：

Coria-Vazquez, Silvia ^{[1
]}

Cruz-Lopez, Samantha ^{[2
]}

Espino-Mier, Katya ^{[2
]}

Lara-Morales, Sonia M. ^{[2
]}

Suarez-Velazquez, Maria F. ^{[2
]}

Lacy-Niebla, Rosa Ma. ^{[3
]}

机构：

[1] Univ Valle Mexico Campus Queretaro, Queretaro, Qro, Mexico

[2] Univ Nacl Autonoma Mexico, Fac Med, Ciudad de Mexico, Mexico

[3] Inst Nacl Cardiol Ignacio Chavez, Ciudad de Mexico, Mexico

来源：

ARCHIVOS DE CARDIOLOGIA DE MEXICO | 2024年

关键词：

Drugs; Adverse drug reaction; Cutaneous adverse drug reaction; Pharmacodermia; SYSTEMIC SYMPTOMS; EOSINOPHILIA; MANAGEMENT;

D O I：

10.24875/ACM.24000107

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cutaneous adverse drug reactions, or pharmacodermias, are the most common form of adverse drug reactions (ADR). It was our interest to know their epidemiological behavior in a tertiary hospital level in Mexico. We stablished the frequency of ADR in 61 infants and adults hospitalized patients and those seen in the outpatient Dermatology Clinic at the National Institute of Cardiology Ignacio Ch & aacute;vez in Mexico City (INCICh) over a period of 10 years. The most frequently diagnosed pharmacodermias were acneiform dermatitis, cutaneous hyperpigmentation and maculopapular exanthema mainly associated to prednisone, hydroxychloroquine, cephalothin, amiodarone and vitamin B-complex, although we registered less frequently more severe and hazardous reactions. These results were consistent with other reports in our country. Multiple drugs administered at a time was an important causative factor for the ADR. It is necessary for every practitioner to develop skills that permit the identification of these dermatoses in order to correctly manage each case and diminish the morbimortality associated.

引用

页数：10